WK298
WK298 is a potent inhibitor of the MDM2/MDMX-p53 interaction with good anti-tumor activity. WK298 can fully activate the p53 pathway by inhibiting the binding of MDM2 and MDMX to p53. The development of WK298 benefited from a deep understanding of the key elements of the p53-MDM2/MDMX interaction structure.
For research use only. We do not sell to patients.
- CAS No.: 1067654-70-9
- Formula: C35H38Cl2N6O
- Molecular Weight:629.62
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 1067654-70-9
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Molecular Weight 629.62
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Formula C35H38Cl2N6O
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SMILES
O=C(N1C[C@H](CC1)N(C)CCCN(C)C)C2=C(C3=C(C4=CC=CC=C4)N=CN3CC5=CC=C(C=C5)Cl)C6=CC=C(Cl)C=C6N2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)