2. Metabolic Enzyme/Protease
  3. Cathepsin
  4. Z-Leu-Leu-Arg-AMC

Z-Leu-Leu-Arg-AMC is a peptide substrate of cathepsin S.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Z-Leu-Leu-Arg-AMC

Z-Leu-Leu-Arg-AMC Chemical Structure

CAS No. : 90468-17-0

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Based on 1 publication(s) in Google Scholar

Z-Leu-Leu-Arg-AMC Related Antibodies

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View All Cathepsin Isoform Specific Products:

View All Isoforms
Cathepsin B Cathepsin C Cathepsin D Cathepsin E Cathepsin K Cathepsin L Cathepsin S

  • Biological Activity

  • Purity & Documentation

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Description

Z-Leu-Leu-Arg-AMC is a peptide substrate of cathepsin S[1].

Molecular Weight

691.82

Formula

C36H49N7O7
CAS No.
Appearance

Solid

Color

White to off-white

Sequence

{Z}-Leu-Leu-Arg-{AMC}
Sequence Shortening

{Z}-LLR-{AMC}
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (144.55 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.4455 mL 7.2273 mL 14.4546 mL
5 mM 0.2891 mL 1.4455 mL 2.8909 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.4455 mL 7.2273 mL 14.4546 mL 36.1366 mL
5 mM 0.2891 mL 1.4455 mL 2.8909 mL 7.2273 mL
10 mM 0.1445 mL 0.7227 mL 1.4455 mL 3.6137 mL
15 mM 0.0964 mL 0.4818 mL 0.9636 mL 2.4091 mL
20 mM 0.0723 mL 0.3614 mL 0.7227 mL 1.8068 mL
25 mM 0.0578 mL 0.2891 mL 0.5782 mL 1.4455 mL
30 mM 0.0482 mL 0.2409 mL 0.4818 mL 1.2046 mL
40 mM 0.0361 mL 0.1807 mL 0.3614 mL 0.9034 mL
50 mM 0.0289 mL 0.1445 mL 0.2891 mL 0.7227 mL
60 mM 0.0241 mL 0.1205 mL 0.2409 mL 0.6023 mL
80 mM 0.0181 mL 0.0903 mL 0.1807 mL 0.4517 mL
100 mM 0.0145 mL 0.0723 mL 0.1445 mL 0.3614 mL
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Z-Leu-Leu-Arg-AMC Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Z-Leu-Leu-Arg-AMC90468-17-0CathepsinInhibitorinhibitorinhibit

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