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Cat. No.: HY-155379

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β-Herpesvirus protease-IN-1

β-Herpesvirus protease-IN-1 (compound 19) is a β-herpesvirus protease inhibitor with IC₅₀s of 2.5 μM and 0.33 μM for HCMVPro and HHV6Pro, respectively.

For research use only. We do not sell to patients.

CAS No.: 3054032-05-9
Formula: C₄₀H₄₅N₇O₄
Molecular Weight:687.83

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (276 KB)

β-Herpesvirus protease-IN-1 Chemical Structure

CAS No.: 3054032-05-9

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

β-Herpesvirus protease-IN-1 (compound 19) is a β-herpesvirus protease inhibitor with IC₅₀s of 2.5 μM and 0.33 μM for HCMVPro and HHV6Pro, respectively^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
HFF	CC₅₀	51 μM Compound: 19	Cytotoxicity against HFF cells assessed as inhibition in cell viability incubated for 5 days by luminescence based analysis Cytotoxicity against HFF cells assessed as inhibition in cell viability incubated for 5 days by luminescence based analysis	[PMID: 37974946]

Chemical Information

CAS No. 3054032-05-9
Molecular Weight 687.83
Formula C₄₀H₄₅N₇O₄
SMILES

O=C1N([C@H](CN1C2=CC=CN(C2=O)[C@H](C3=CN(N=C3C4=C(C=CC=C4)C)C5CCCC5)C6=CC=C(C=C6)C)C(NC78C(NC(CC8)CC7)=O)=O)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (276 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Shuhei Yoshida, et al. Peptide-to-Small Molecule: Discovery of Non-Covalent, Active-Site Inhibitors of β-Herpesvirus Proteases. ACS Med. Chem. Lett.October 27, 2023.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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