1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite Xanthine Oxidase
  3. Oxypurinol

Oxypurinol  (Synonyms: Oxipurinol)

Cat. No.: HY-19657 Purity: 99.54%
COA Handling Instructions

Oxipurinol (Oxipurinol), the major active metabolite of Allopurinol, is an inhibitor of xanthine oxidase. Oxipurinol can be used to regulate blood urate levels and treat gout.

For research use only. We do not sell to patients.

Oxypurinol Chemical Structure

Oxypurinol Chemical Structure

CAS No. : 2465-59-0

Size Price Stock Quantity
Solution
10 mM * 1 mL in DMSO USD 88 In-stock
Solid
50 mg USD 80 In-stock
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This product is a controlled substance and not for sale in your territory.

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Based on 1 publication(s) in Google Scholar

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Description

Oxipurinol (Oxipurinol), the major active metabolite of Allopurinol, is an inhibitor of xanthine oxidase. Oxipurinol can be used to regulate blood urate levels and treat gout[1].

IC50 & Target

Xanthine oxidoreductase[1]

In Vitro

Allopurinol is rapidly metabolized (half-life approximately 1 h) to its active metabolite oxypurinol. Oxypurinol is an inhibitor of xanthine oxidoreductase and has a considerably longer elimination half-life (approximately 23 h)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
Molecular Weight

152.11

Appearance

Solid

Formula

C5H4N4O2

CAS No.
SMILES

O=C1C2=C(NN=C2)NC(N1)=O

Structure Classification
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : < 1 mg/mL (insoluble or slightly soluble)

In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline

    Solubility: ≥ 1.25 mg/mL (8.22 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in Saline)

    Solubility: ≥ 1.25 mg/mL (8.22 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% Corn Oil

    Solubility: ≥ 1.25 mg/mL (8.22 mM); Clear solution

*All of the co-solvents are available by MedChemExpress (MCE).
Purity & Documentation

Purity: 99.54%

References
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Product Name:
Oxypurinol
Cat. No.:
HY-19657
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