1. Metabolic Enzyme/Protease
  2. Drug Metabolite Endogenous Metabolite Xanthine Oxidase
  3. Oxypurinol

Oxypurinol  (Synonyms: Oxipurinol)

Cat. No.: HY-19657 Purity: ≥98.0%
COA Handling Instructions

Oxipurinol (Oxipurinol), the major active metabolite of Allopurinol, is an inhibitor of xanthine oxidase. Oxipurinol can be used to regulate blood urate levels and treat gout.

For research use only. We do not sell to patients.

Oxypurinol Chemical Structure

Oxypurinol Chemical Structure

CAS No. : 2465-59-0

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Based on 1 publication(s) in Google Scholar

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Description

Oxipurinol (Oxipurinol), the major active metabolite of Allopurinol, is an inhibitor of xanthine oxidase. Oxipurinol can be used to regulate blood urate levels and treat gout[1].

IC50 & Target

Xanthine oxidoreductase[1]

In Vitro

Allopurinol is rapidly metabolized (half-life approximately 1 h) to its active metabolite oxypurinol. Oxypurinol is an inhibitor of xanthine oxidoreductase and has a considerably longer elimination half-life (approximately 23 h)[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial
Molecular Weight

152.11

Formula

C5H4N4O2

CAS No.
Appearance

Solid

Color

White to yellow

SMILES

O=C1C2=C(NN=C2)NC(N1)=O

Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : < 1 mg/mL (insoluble or slightly soluble)

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Purity & Documentation
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    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Oxypurinol
Cat. No.:
HY-19657
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