1-Docosapentaenoyl-2-hydroxy-sn-glycero-3-phosphatidylcholine
Based on 1 Customer Validation
1-Docosapentaenoyl-2-hydroxy-sn-glycero-3-phosphatidylcholine is an ester product.
For research use only. We do not sell to patients.
- Purity : 99%
- CAS No.: 2201069-26-1
- Formula: C30H52NO7P
- Molecular Weight:569.71
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Description
Chemical Information
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CAS No. 2201069-26-1
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Appearance Solid
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Molecular Weight 569.71
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Formula C30H52NO7P
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Color White to off-white
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SMILES
CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCCCC(OC[C@@H](O)COP(OCC[N+](C)(C)C)([O-])=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
Ethanol : 100 mg/mL (175.53 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo:
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% EtOH 40% PEG300 5% Tween-80 45% Saline
Solubility: ≥ 2.5 mg/mL (4.39 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL EtOH stock solution (25.0 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.
Preparation of Saline: Dissolve 0.9 g sodium chloride in ddH₂O and dilute to 100 mL to obtain a clear Saline solution.
Add each solvent one by one: 10% EtOH 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 2.5 mg/mL (4.39 mM); Clear solution
This protocol yields a clear solution of ≥ 2.5 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL EtOH stock solution (25.0 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Add each solvent one by one: 10% EtOH 90% Corn Oil
Solubility: 2.5 mg/mL (4.39 mM); Suspended solution; Need ultrasonic
This protocol yields a suspended solution of 2.5 mg/mL. Suspended solution can be used for oral and intraperitoneal injection.
Taking 1 mL working solution as an example, add 100 μL EtOH stock solution (25.0 mg/mL) to 900 μL Corn oil, and mix evenly.
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
Purity & Documentation
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Data Sheet (237 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| Ethanol | 1 mM | 1.7553 mL | 8.7764 mL | 17.5528 mL | 43.8820 mL |
| 5 mM | 0.3511 mL | 1.7553 mL | 3.5106 mL | 8.7764 mL | |
| 10 mM | 0.1755 mL | 0.8776 mL | 1.7553 mL | 4.3882 mL | |
| 15 mM | 0.1170 mL | 0.5851 mL | 1.1702 mL | 2.9255 mL | |
| 20 mM | 0.0878 mL | 0.4388 mL | 0.8776 mL | 2.1941 mL | |
| 25 mM | 0.0702 mL | 0.3511 mL | 0.7021 mL | 1.7553 mL | |
| 30 mM | 0.0585 mL | 0.2925 mL | 0.5851 mL | 1.4627 mL | |
| 40 mM | 0.0439 mL | 0.2194 mL | 0.4388 mL | 1.0970 mL | |
| 50 mM | 0.0351 mL | 0.1755 mL | 0.3511 mL | 0.8776 mL | |
| 60 mM | 0.0293 mL | 0.1463 mL | 0.2925 mL | 0.7314 mL | |
| 80 mM | 0.0219 mL | 0.1097 mL | 0.2194 mL | 0.5485 mL | |
| 100 mM | 0.0176 mL | 0.0878 mL | 0.1755 mL | 0.4388 mL |