2. GPCR/G Protein Cell Cycle/DNA Damage
  3. Mitosis LPL Receptor
  4. 1-Oleoyl lysophosphatidic acid sodium

1-Oleoyl lysophosphatidic acid sodium  (Synonyms: 1-Oleoyl-sn-glycero-3-phosphate sodium; 1-Oleoyl-LPA sodium)

Cat. No.: HY-107614 Purity: 99.96%
COA
SDS
Handling Instructions Technical Support

1-Oleoyl lysophosphatidic acid (1-Oleoyl-sn-glycero-3-phosphate) sodium, a potent bioactive phospholipid, is a LPA receptor activator. 1-Oleoyl lysophosphatidic acid sodium can promote mitosis by inducing DNA synthesis. 1-Oleoyl lysophosphatidic acid sodium is also involved in normal and pathological emotional responses, including anxiety and depression.

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CAS No. : 325465-93-8

사이즈 가격 재고 수량
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in Water
ready for reconstitution
 해외재고보유
Solution
10 mM * 1 mL in Water 해외재고보유
Solid
5 mg 해외재고보유
10 mg 해외재고보유
25 mg 해외재고보유
50 mg 해외재고보유
100 mg 해외재고보유
200 mg   견적 받기  
500 mg   견적 받기  

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고객리뷰

Based on 3 publication(s) in Google Scholar

Other Forms of 1-Oleoyl lysophosphatidic acid sodium:

1-Oleoyl lysophosphatidic acid sodium Related Antibodies

Top Publications Citing Use of Products

    1-Oleoyl lysophosphatidic acid sodium purchased from MedChemExpress. Usage Cited in: Neurobiol Stress. 2024 Apr 4:30:100632.  [Abstract]

    Western blot analysis showed that in the brains of mice, LPA (1-Oleoyl lysophosphatidic acid) injection into the lateral ventricles affected the expression of synaptic-related proteins in the hippocampus

    View All LPL Receptor Isoform Specific Products:

    View All Isoforms
    LPAR1 LPAR2 LPAR3 LPAR5 S1PR1 S1PR2 S1PR3 S1PR4 S1PR5

    • Biological Activity

    • 순도&문서

    • References

    • 고객리뷰

    제품 설명

    1-Oleoyl lysophosphatidic acid (1-Oleoyl-sn-glycero-3-phosphate) sodium, a potent bioactive phospholipid, is a LPA receptor activator. 1-Oleoyl lysophosphatidic acid sodium can promote mitosis by inducing DNA synthesis. 1-Oleoyl lysophosphatidic acid sodium is also involved in normal and pathological emotional responses, including anxiety and depression[1][2][3].

    IC50 & Target

    LPA receptor[1]
    In Vitro

    1-Oleoyl lysophosphatidic acid (0.1-10 μM) sodium elicits an acute rise of [Ca2+]i in rat and rabbit osteoclasts[2].
    1-Oleoyl lysophosphatidic acid (5 μM) sodium induces retraction of osteoclast lamellipodia[2].

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    1-Oleoyl lysophosphatidic acid sodium Related Antibodies
    분자량

    458.50

    화학식

    C21H40NaO7P
    CAS No.
    Appearance

    Solid

    Color

    White to off-white

    SMILES

    CCCCCCCC/C=C\CCCCCCCC(OC[C@@H](O)COP(O)(O[Na])=O)=O
    선적

    Room temperature in continental US; may vary elsewhere.
    보관

    -20°C, sealed storage, away from moisture

    *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

    용액&용해도
    In Vitro: 

    H2O : 25 mg/mL (54.53 mM; Need ultrasonic)

    DMSO : 1.85 mg/mL (4.03 mM; ultrasonic and warming and adjust pH to 5 with HCl and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

    Preparing
    Stock Solutions
    Concentration Solvent Mass 1 mg 5 mg 10 mg
    1 mM 2.1810 mL 10.9051 mL 21.8103 mL
    5 mM 0.4362 mL 2.1810 mL 4.3621 mL
    View the Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

    • 몰농도 계산기

    • 농도 희석 계산기

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    This equation is commonly abbreviated as: C1V1 = C2V2

    Concentration (start)

    C1

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    Volume (start)

    V1

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    Concentration (final)

    C2

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    Volume (final)

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    In Vivo Dissolution Calculator
    Please enter the basic information of animal experiments:

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    Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
    Calculation results:
    Working solution concentration: mg/mL
    This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
    The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
    순도&문서

    Purity: 99.96%

    SDS (420 KB)

    COA (240 KB) HNMR (267 KB) RP-HPLC (249 KB) MS (71 KB)

    Handling Instructions (2659 KB)
    References

    Complete Stock Solution Preparation Table

    * Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
    Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

    Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
    DMSO / H2O 1 mM 2.1810 mL 10.9051 mL 21.8103 mL 54.5256 mL
    H2O 5 mM 0.4362 mL 2.1810 mL 4.3621 mL 10.9051 mL
    10 mM 0.2181 mL 1.0905 mL 2.1810 mL 5.4526 mL
    15 mM 0.1454 mL 0.7270 mL 1.4540 mL 3.6350 mL
    20 mM 0.1091 mL 0.5453 mL 1.0905 mL 2.7263 mL
    25 mM 0.0872 mL 0.4362 mL 0.8724 mL 2.1810 mL
    30 mM 0.0727 mL 0.3635 mL 0.7270 mL 1.8175 mL
    40 mM 0.0545 mL 0.2726 mL 0.5453 mL 1.3631 mL
    50 mM 0.0436 mL 0.2181 mL 0.4362 mL 1.0905 mL

    * Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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    1-Oleoyl lysophosphatidic acid sodium Related Classifications

    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    1-Oleoyl lysophosphatidic acid325465-93-81-Oleoyl-sn-glycero-3-phosphate1-Oleoyl-LPAMitosisLPL ReceptorLysophospholipid ReceptorLPAmitosisDNAanxietydepressionInhibitorinhibitorinhibit

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    상품명:
    1-Oleoyl lysophosphatidic acid sodium
    Cat. No.:
    HY-107614
    수량:
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