2. GPCR/G Protein
  3. LPL Receptor
  4. 1-Oleoyl lysophosphatidic acid sodium

1-Oleoyl lysophosphatidic acid sodium  (Synonyms: 1-Oleoyl-sn-glycero-3-phosphate sodium; 1-Oleoyl-LPA sodium)

Cat. No.: HY-107614 Purity: ≥98.0%
COA Handling Instructions

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1-Oleoyl lysophosphatidic acid (1-Oleoyl-sn-glycero-3-phosphate) sodium, a potent bioactive phospholipid, is a LPA receptor activator. 1-Oleoyl lysophosphatidic acid sodium can promote mitosis by inducing DNA synthesis. 1-Oleoyl lysophosphatidic acid sodium is also involved in normal and pathological emotional responses, including anxiety and depression.

For research use only. We do not sell to patients.

1-Oleoyl lysophosphatidic acid sodium Chemical Structure

1-Oleoyl lysophosphatidic acid sodium Chemical Structure

CAS No. : 325465-93-8

Size Price Stock Quantity
5 mg USD 187 In-stock
10 mg USD 220 In-stock
25 mg USD 440 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of 1-Oleoyl lysophosphatidic acid sodium:

1-Oleoyl lysophosphatidic acid sodium Related Antibodies

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Description

1-Oleoyl lysophosphatidic acid (1-Oleoyl-sn-glycero-3-phosphate) sodium, a potent bioactive phospholipid, is a LPA receptor activator. 1-Oleoyl lysophosphatidic acid sodium can promote mitosis by inducing DNA synthesis. 1-Oleoyl lysophosphatidic acid sodium is also involved in normal and pathological emotional responses, including anxiety and depression[1][2][3].

IC50 & Target

LPA receptor[1]
In Vitro

1-Oleoyl lysophosphatidic acid (0.1-10 μM) sodium elicits an acute rise of [Ca2+]i in rat and rabbit osteoclasts[2].
? 1-Oleoyl lysophosphatidic acid (5 μM) sodium induces retraction of osteoclast lamellipodia[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

1-Oleoyl lysophosphatidic acid sodium Related Antibodies
Molecular Weight

458.50

Formula

C21H40NaO7P
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CCCCCCCC/C=C\CCCCCCCC(OC[C@@H](O)COP(O)(O[Na])=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (218.10 mM; Need ultrasonic)

DMSO : 1.85 mg/mL (4.03 mM; ultrasonic and warming and adjust pH to 5 with HCl and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1810 mL 10.9051 mL 21.8103 mL
5 mM 0.4362 mL 2.1810 mL 4.3621 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Purity: ≥98.0%

COA (240 KB) HNMR (270 KB) CNMR (245 KB) MS (84 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO / H2O 1 mM 2.1810 mL 10.9051 mL 21.8103 mL 54.5256 mL
H2O 5 mM 0.4362 mL 2.1810 mL 4.3621 mL 10.9051 mL
10 mM 0.2181 mL 1.0905 mL 2.1810 mL 5.4526 mL
15 mM 0.1454 mL 0.7270 mL 1.4540 mL 3.6350 mL
20 mM 0.1091 mL 0.5453 mL 1.0905 mL 2.7263 mL
25 mM 0.0872 mL 0.4362 mL 0.8724 mL 2.1810 mL
30 mM 0.0727 mL 0.3635 mL 0.7270 mL 1.8175 mL
40 mM 0.0545 mL 0.2726 mL 0.5453 mL 1.3631 mL
50 mM 0.0436 mL 0.2181 mL 0.4362 mL 1.0905 mL
60 mM 0.0364 mL 0.1818 mL 0.3635 mL 0.9088 mL
80 mM 0.0273 mL 0.1363 mL 0.2726 mL 0.6816 mL
100 mM 0.0218 mL 0.1091 mL 0.2181 mL 0.5453 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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1-Oleoyl lysophosphatidic acid sodium Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

1-Oleoyl lysophosphatidic acid325465-93-81-Oleoyl-sn-glycero-3-phosphate1-Oleoyl-LPALPL ReceptorLysophospholipid ReceptorLPAmitosisDNAanxietydepressionInhibitorinhibitorinhibit

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