11β-HSD1-IN-16
Based on 1 Customer Validation
11β-HSD1-IN-16 is an inhibitor of the 11β-hydroxysteroid dehydrogenase HSD11B1, demonstrating an IC of 0.34 μM, making it a valuable tool for research on neuropathic pain, inflammatory pain, and occipital neuralgia.
For research use only. We do not sell to patients.
- Purity: 99.03%
- CAS No.: 314051-55-3
- Formula: C16H13F3N4O2
- Molecular Weight:350.30
-
Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Chemical Information
-
CAS No. 314051-55-3
-
Appearance Solid
-
Molecular Weight 350.30
-
Formula C16H13F3N4O2
-
Color Light yellow to light brown
-
SMILES
O=C(N1CCCC1)C2=NN3C(N=C(C4=CC=CO4)C=C3C(F)(F)F)=C2
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 25 mg/mL (71.37 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (246 KB)
-
SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
-
Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.8547 mL | 14.2735 mL | 28.5470 mL | 71.3674 mL |
| 5 mM | 0.5709 mL | 2.8547 mL | 5.7094 mL | 14.2735 mL | |
| 10 mM | 0.2855 mL | 1.4273 mL | 2.8547 mL | 7.1367 mL | |
| 15 mM | 0.1903 mL | 0.9516 mL | 1.9031 mL | 4.7578 mL | |
| 20 mM | 0.1427 mL | 0.7137 mL | 1.4273 mL | 3.5684 mL | |
| 25 mM | 0.1142 mL | 0.5709 mL | 1.1419 mL | 2.8547 mL | |
| 30 mM | 0.0952 mL | 0.4758 mL | 0.9516 mL | 2.3789 mL | |
| 40 mM | 0.0714 mL | 0.3568 mL | 0.7137 mL | 1.7842 mL | |
| 50 mM | 0.0571 mL | 0.2855 mL | 0.5709 mL | 1.4273 mL | |
| 60 mM | 0.0476 mL | 0.2379 mL | 0.4758 mL | 1.1895 mL |