2-Bromo-1,4-difluorobenzene
Based on 1 Customer Validation
2-Bromo-1,4-difluorobenzene is a fluorine-substituted haloarene and serves as an inexpensive, large-volume organic synthesis raw material. 2-Bromo-1,4-difluorobenzene can be used to prepare 1,4-difluoroanthraquinone, which is a precursor of Ametantrone (HY-13550). 2-Bromo-1,4-difluorobenzene can be used as a biomaterial or organic compound in life science-related research.
For research use only. We do not sell to patients.
- Purity : 99.97%
- CAS No.: 399-94-0
- Formula: C6H3BrF2
- Molecular Weight:192.99
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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1,4-Bis(trifluoromethyl)benzene (Standard)Organic Compound
Biological Activity
Description
In Vitro
2-Bromo-1,4-difluorobenzene can be used for the synthesis of 1,4-difluoroanthraquinone, which can be further utilized to prepare antitumor drugs such as Mitoxantrone (HY-13502) and Amsacrine (HY-13551). It also serves as the starting material for the total synthesis of the oral HIF-2α inhibitor Belzutifan (HY-125840)[1][2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS No. 399-94-0
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Appearance Liquid (Density: 1.708 g/cm3)
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Molecular Weight 192.99
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Formula C6H3BrF2
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Color Colorless to light yellow
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SMILES
FC1=CC=C(F)C=C1Br
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 200 mg/mL (1036.32 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (279 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.1816 mL | 25.9081 mL | 51.8162 mL | 129.5404 mL |
| 5 mM | 1.0363 mL | 5.1816 mL | 10.3632 mL | 25.9081 mL | |
| 10 mM | 0.5182 mL | 2.5908 mL | 5.1816 mL | 12.9540 mL | |
| 15 mM | 0.3454 mL | 1.7272 mL | 3.4544 mL | 8.6360 mL | |
| 20 mM | 0.2591 mL | 1.2954 mL | 2.5908 mL | 6.4770 mL | |
| 25 mM | 0.2073 mL | 1.0363 mL | 2.0726 mL | 5.1816 mL | |
| 30 mM | 0.1727 mL | 0.8636 mL | 1.7272 mL | 4.3180 mL | |
| 40 mM | 0.1295 mL | 0.6477 mL | 1.2954 mL | 3.2385 mL | |
| 50 mM | 0.1036 mL | 0.5182 mL | 1.0363 mL | 2.5908 mL | |
| 60 mM | 0.0864 mL | 0.4318 mL | 0.8636 mL | 2.1590 mL | |
| 80 mM | 0.0648 mL | 0.3239 mL | 0.6477 mL | 1.6193 mL | |
| 100 mM | 0.0518 mL | 0.2591 mL | 0.5182 mL | 1.2954 mL |
2-Bromo-1,4-difluorobenzene Related Classifications
HY-79541 Related Classifications
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