2-Bromo-4-fluoroanisole
Based on 1 Customer Validation
2-Bromo-4-fluoroanisole is an important intermediate in organic synthesis. 2-Bromo-4-fluoroanisole can be used in the research of diabetic complications (including blindness).
For research use only. We do not sell to patients.
- Purity: 99.69%
- CAS No.: 452-08-4
- Formula: C7H6BrFO
- Molecular Weight:205.03
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Storage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Chemical Information
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CAS No. 452-08-4
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Appearance Liquid (Density: 1.581 g/cm3)
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Molecular Weight 205.03
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Formula C7H6BrFO
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Color Colorless to light yellow
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SMILES
COC1=C(Br)C=C(F)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 200 mg/mL (975.47 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
[1]. de la Fuente JA, et al. Synthesis, activity, and molecular modeling studies of novel human aldose reductase inhibitors based on a marine natural product. J Med Chem. 2003 Nov 20;46(24):5208-21. [Content Brief]
[2]. Edwards JP, et al. 5-Aryl-1,2-dihydro-5H-chromeno[3,4-f]quinolines as potent, orally active, nonsteroidal progesterone receptor agonists: the effect of D-ring substituents. J Med Chem. 1998 Jan 29;41(3):303-10. [Content Brief]
[3]. Betageri R, et al. Trifluoromethyl group as a pharmacophore: effect of replacing a CF3 group on binding and agonist activity of a glucocorticoid receptor ligand. Bioorg Med Chem Lett. 2005 Nov 1;15(21):4761-9. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.8773 mL | 24.3867 mL | 48.7734 mL | 121.9334 mL |
| 5 mM | 0.9755 mL | 4.8773 mL | 9.7547 mL | 24.3867 mL | |
| 10 mM | 0.4877 mL | 2.4387 mL | 4.8773 mL | 12.1933 mL | |
| 15 mM | 0.3252 mL | 1.6258 mL | 3.2516 mL | 8.1289 mL | |
| 20 mM | 0.2439 mL | 1.2193 mL | 2.4387 mL | 6.0967 mL | |
| 25 mM | 0.1951 mL | 0.9755 mL | 1.9509 mL | 4.8773 mL | |
| 30 mM | 0.1626 mL | 0.8129 mL | 1.6258 mL | 4.0644 mL | |
| 40 mM | 0.1219 mL | 0.6097 mL | 1.2193 mL | 3.0483 mL | |
| 50 mM | 0.0975 mL | 0.4877 mL | 0.9755 mL | 2.4387 mL | |
| 60 mM | 0.0813 mL | 0.4064 mL | 0.8129 mL | 2.0322 mL | |
| 80 mM | 0.0610 mL | 0.3048 mL | 0.6097 mL | 1.5242 mL | |
| 100 mM | 0.0488 mL | 0.2439 mL | 0.4877 mL | 1.2193 mL |