2-O-Ethyl PAF C-16
Based on 1 Customer Validation
2-O-Ethyl PAF C-16 is a homolog of PAF and a competitive ligand for PAF receptor (Platelet-activating Factor Receptor (PAFR)). 2-O-Ethyl PAF C-16 inhibits the binding of the PAF antagonist WEB 2086 (HY-108634) to the PAF receptor with an IC50 of 21 nM.
For research use only. We do not sell to patients.
- Purity : 99.9%
- CAS No.: 78858-42-1
- Formula: C26H56NO6P
- Molecular Weight:509.70
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Storage:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
Description
Cellular Effect
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| CCRF-CEM | IC50 |
2.9 μg/mL
Compound: 24
|
In vitro inhibition of CCRF-CEM cell proliferation
In vitro inhibition of CCRF-CEM cell proliferation
|
[PMID: 3783607] |
Chemical Information
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CAS No. 78858-42-1
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Appearance Oil
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Molecular Weight 509.70
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Formula C26H56NO6P
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Color White to off-white
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SMILES
CCCCCCCCCCCCCCCCOC[C@@H](OCC)COP(OCC[N+](C)(C)C)([O-])=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
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Data Sheet (261 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)