(2R,4R)-LY3372689
O-GlcNAcase-IN-4 is a O-GlcNAcase inhibitor extracted from patent WO2018140299A1 Formulaic Ic. O-GlcNAcase-IN-4 can be used for the research of neurodegenerative diseases and disorders, such as Alzheimer's disease.
For research use only. We do not sell to patients.
- CAS No.: 3085990-58-2
- Formula: C16H22FN5O3S
- Molecular Weight:383.44
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
O-GlcNAcase[1]
Chemical Information
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CAS No. 3085990-58-2
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Molecular Weight 383.44
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Formula C16H22FN5O3S
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SMILES
CC(NC1=NC(F)=C(S1)CN2[C@@H](C[C@@H](CC2)OCC3=NOC(C)=N3)C)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Alzheimer’s Disease Modeling
Alzheimer’s Disease (AD) is a neurodegenerative disorder characterized by a progressive decline in cognitive functions and loss of specific types of neurons and synapses. Alzheimer's symptoms can be simulated in mice by injecting drugs (such as Aβ) or genetically modified.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)