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Cat. No.: HY-12772S6

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(2S,4R)-Hydroxy Itraconazole-d₆

Name: (2S,4R)-Hydroxy Itraconazole-d6
Brand: MedChemExpress
SKU: HY-12772S6
Availability: PreOrder

(Synonyms: (2S,4R)-R-63373-d₆)

(2R,4S)-Hydroxy Itraconazole-d₆ ((2R,4S)-R-63373-d₆) is the deuterated-labeled (2S,4R)-Hydroxy Itraconazole (HY-12772). (2S,4R)-Hydroxy Itraconazole ((2S,4R)-R-63373) is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent.

For research use only. We do not sell to patients.

Formula: C₃₅H₃₂D₆Cl₂N₈O₅
Molecular Weight:727.67

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

(2S,4R)-Hydroxy Itraconazole-d₆ Chemical Structure

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
- Application
Chemical Information
Purity & Documentation
References
Calculators
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Classifications
Bioz

Biological Activity

Description

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .

Application

1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

Chemical Information

Unlabeled CAS 199797-93-8
Molecular Weight 727.67
Formula C₃₅H₃₂D₆Cl₂N₈O₅
SMILES

ClC1=CC(Cl)=C([C@]2(O[C@H](COC3=CC=C(N4CCN(C5=CC=C(N6C([2H])=NN(C([2H])(C(O)(C([2H])([2H])[2H])[2H])C)C6=O)C=C5)CC4)C=C3)CO2)CN7N=CN=C7)C=C1
Synonyms

(2S,4R)-R-63373-d₆
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Mino Y, et al. Hydroxy-itraconazole pharmacokinetics is similar to that of itraconazole in immunocompromised patients receiving oral solution of itraconazole. Clin Chim Acta. 2013 Jan 16;415:128-32. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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Biological Activity
- Description
- In Vitro
- Application
Chemical Information
Purity & Documentation
References

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(2S,4R)-Hydroxy Itraconazole-d6