3-Hydroxypicolinic acid, matrix substance for MALDI-MS  (Synonyms: 3-HPA)

3-Hydroxypicolinic acid, matrix substance for MALDI-MS is a matrix. 3-Hydroxypicolinic acid, matrix substance for MALDI-MS coordinates with metal ions such as copper to form complexes with cytotoxic and antimycobacterial activity. 3-Hydroxypicolinic acid, matrix substance for MALDI-MS is used for the analysis of oligodeoxynucleotides in matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF MS). 3-Hydroxypicolinic acid, matrix substance for MALDI-MS is useful for nucleic acid analysis and anti-tuberculosis compound development^[1][2][3].

others

139.11

C₆H₅NO₃

874-24-8

Solid

White to off-white

O=C(C1=NC=CC=C1O)O

Room temperature in continental US; may vary elsewhere.

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

• [1]. Zhou L, et al. A mixed matrix of 3-hydroxypicolinic acid and pyrazinecarboxylic acid for matrix-assisted laser desorption/ionization time-of-flight mass spectrometry of oligodeoxynucleotides. Rapid Commun Mass Spectrom. 2004;18(7):787-94.  [Content Brief]

  [2]. Brockman FJ, et al. Isolation and characterization of quinoline-degrading bacteria from subsurface sediments. Appl Environ Microbiol. 1989 Apr;55(4):1029-32.  [Content Brief]

  [3]. do Couto Almeida J, et al. Synthesis, cytotoxic and antitubercular activities of copper (II) complexes with heterocyclic bases and 3-hydroxypicolinic acid. Inorganica Chimica Acta, 2016, 446: 87-92.