306-O12B-3
Based on 1 Customer Validation
306-O12B-3 is a lipidoid that can efficiently deliver ASO both in vitro and in vivo. 306-O12B-3 is used to transport small molecule drugs across the blood-brain barrier (BBB).
For research use only. We do not sell to patients.
- Purity : 98.04%
- Formula: C46H91N3O6S6
- Molecular Weight:974.62
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Storage:
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Biological Activity
Description
Chemical Information
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Appearance Liquid
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Molecular Weight 974.62
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Formula C46H91N3O6S6
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Color Colorless to light yellow
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SMILES
CCCCCCCCSSCCOC(CCN(CCCN(C)CCCNCCC(OCCSSCCCCCCCC)=O)CCC(OCCSSCCCCCCCC)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Solvent & Solubility
In Vitro:
Ethanol : ≥ 100 mg/mL (102.60 mM)
DMSO : 3.33 mg/mL (3.42 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO / Ethanol | 1 mM | 1.0260 mL | 5.1302 mL | 10.2604 mL | 25.6510 mL |
| Ethanol | 5 mM | 0.2052 mL | 1.0260 mL | 2.0521 mL | 5.1302 mL |
| 10 mM | 0.1026 mL | 0.5130 mL | 1.0260 mL | 2.5651 mL | |
| 15 mM | 0.0684 mL | 0.3420 mL | 0.6840 mL | 1.7101 mL | |
| 20 mM | 0.0513 mL | 0.2565 mL | 0.5130 mL | 1.2826 mL | |
| 25 mM | 0.0410 mL | 0.2052 mL | 0.4104 mL | 1.0260 mL | |
| 30 mM | 0.0342 mL | 0.1710 mL | 0.3420 mL | 0.8550 mL | |
| 40 mM | 0.0257 mL | 0.1283 mL | 0.2565 mL | 0.6413 mL | |
| 50 mM | 0.0205 mL | 0.1026 mL | 0.2052 mL | 0.5130 mL | |
| 60 mM | 0.0171 mL | 0.0855 mL | 0.1710 mL | 0.4275 mL | |
| 80 mM | 0.0128 mL | 0.0641 mL | 0.1283 mL | 0.3206 mL | |
| 100 mM | 0.0103 mL | 0.0513 mL | 0.1026 mL | 0.2565 mL |