4-[2-(Trimethylsilyl)ethynyl]benzaldehyde
Based on 1 Customer Validation
4-[2-(Trimethylsilyl)ethynyl]benzaldehyde is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- CAS No.: 77123-57-0
- Formula: C12H14OSi
- Molecular Weight:202.33
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Storage:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
All PROTAC Linkers Isoforms
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Biological Activity
PROTACs contain two different ligands connected by a linker; one is a ligand for an E366 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 77123-57-0
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Appearance Solid
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Molecular Weight 202.33
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Formula C12H14OSi
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Color Off-white to light brown
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SMILES
O=CC1=CC=C(C#C[Si](C)(C)C)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Purity & Documentation
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Data Sheet (238 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)