4-Arm-PEG20000-Acrylamide
4-Arm-PEG20000-Acrylamide is a four-armed PEG derivative. The core structure of 4-Arm-PEG20000-Acrylamide consists of four PEG chains, each modified with an acrylamide group at its end. 4-Arm-PEG20000-Acrylamide can be used for bioconjugation and drug delivery.
For research use only. We do not sell to patients.
- CAS No.: 1818880-26-0
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
The structure of PEG-Acrylamide comprises two key parts that work synergistically:
Acrylamide: Under free radical initiators or UV irradiation, the acrylamide double bonds can rapidly initiate polymerization, forming a stable three-dimensional hydrogel network; it can also react with molecules containing thiol (-SH) groups through click chemistry or Michael addition.
PEG chain: Acting as a hydrophilic spacer, it forms a hydration layer on the particle surface, reducing non-specific adsorption and immune system recognition and clearance, thus prolonging the carrier's circulation time in vivo.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1818880-26-0
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SMILES
C=CC(NCCOCCOCC(COCCOCCNC(C=C)=O)(COCCOCCNC(C=C)=O)COCCOCCNC(C=C)=O)=O.[n].[n].[n].[n]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)