5,8-Dihydroxy-3',4',6,7-tetramethoxyflavone
Based on 1 Customer Validation
5,8-Dihydroxy-3',4',6,7-tetramethoxyflavone (Compound 8) is a flavonoid with anticancer activity. 5,8-Dihydroxy-3',4',6,7-tetramethoxyflavone can be isolated from Euryops arabicus.
For research use only. We do not sell to patients.
- Purity: 97.75%
- CAS No.: 683278-67-3
- Formula: C19H18O8
- Molecular Weight:374.34
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Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Biological Activity
Description
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | IC50 |
45 μM
Compound: 8
|
Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
Antiproliferative activity against human HepG2 cells after 48 hrs by MTT assay
|
[PMID: 23800391] |
| MCF7 | IC50 |
35 μM
Compound: 8
|
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
Antiproliferative activity against human MCF7 cells after 48 hrs by MTT assay
|
[PMID: 23800391] |
| Vero | IC50 |
100 μM
Compound: 8
|
Antiproliferative activity against african green monkey Vero cells after 48 hrs by MTT assay
Antiproliferative activity against african green monkey Vero cells after 48 hrs by MTT assay
|
[PMID: 23800391] |
| WI-38 | IC50 |
95 μM
Compound: 8
|
Antiproliferative activity against human WI38 cells after 48 hrs by MTT assay
Antiproliferative activity against human WI38 cells after 48 hrs by MTT assay
|
[PMID: 23800391] |
Chemical Information
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CAS No. 683278-67-3
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Appearance Solid
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Molecular Weight 374.34
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Formula C19H18O8
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Color Light yellow to yellow
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SMILES
O=C1C=C(C2=CC(OC)=C(OC)C=C2)OC3=C(C(OC)=C(C(O)=C13)OC)O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)