6α,11,12-Trihydroxy-7β,20-epoxy-8,11,13-abietatriene
6α,11,12-Trihydroxy-7β,20-epoxy-8,11,13-abietatriene (Compound 6) is a diterpenoid found in Premna obtusifolia with antibacterial activity. 6α,11,12-Trihydroxy-7β,20-epoxy-8,11,13-abietatriene can significantly inhibit the release of the inflammatory mediator NO, with an IC50 value of 29.1 μM. 6α,11,12-Trihydroxy-7β,20-epoxy-8,11,13-abietatriene can be used for the researches of infection and inflammation.
For research use only. We do not sell to patients.
- CAS No.: 1353042-00-8
- Formula: C20H28O4
- Molecular Weight:332.43
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
6α,11,12-Trihydroxy-7β,20-epoxy-8,11,13-abietatriene exhibits antibacterial against Bacillus subtilis, Staphylococcus aureus, Enterococcus faecalis, Methicillin-resistant Staphylococcus aureus (MRSA), and Vancomycin-resistant Enterococcus faecalis (VRE) (MIC = 37.5 μg/mL)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1353042-00-8
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Molecular Weight 332.43
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Formula C20H28O4
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SMILES
OC1=C2[C@@]34[C@@](C(C)(CCC4)C)([H])[C@H]([C@@](OC3)([H])C2=CC(C(C)C)=C1O)O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
6α,11,12-Trihydroxy-7β,20-epoxy-8,11,13-abietatriene Related Classifications
HY-N16665 Related Classifications
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