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Cat. No.: HY-N12250

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7-Deoxynarciclasine

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7-Deoxynarciclasine (compound 2b) can be isolated from Hymenocallis littoralis. 7-Deoxynarciclasine inhibits the cancer cell growth.

For research use only. We do not sell to patients.

Purity: 98.61%
CAS No.: 19622-83-4
Formula: C₁₄H₁₃NO₆
Molecular Weight:291.26

Storage:

Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month

7-Deoxynarciclasine Chemical Structure

CAS No.: 19622-83-4

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

7-Deoxynarciclasine (compound 2b) can be isolated from Hymenocallis littoralis. 7-Deoxynarciclasine inhibits the cancer cell growth^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
BXPC-3	GI₅₀	0.07 μg/mL Compound: 1b	Cytotoxicity against human sBxPC-3 cells Cytotoxicity against human sBxPC-3 cells	[PMID: 15730244]
DU-145	GI₅₀	0.051 μg/mL Compound: 1b	Cytotoxicity against human DU145 cells Cytotoxicity against human DU145 cells	[PMID: 15730244]
DU-145	GI₅₀	0.062 μg/mL Compound: 2b	Growth inhibition of human DU145 cells Growth inhibition of human DU145 cells	[PMID: 16441059]
Huh-7	CC₅₀	7.2 μM Compound: 1	Cytotoxicity against human Huh7.5 cells treated after 96 hrs by MTT assay Cytotoxicity against human Huh7.5 cells treated after 96 hrs by MTT assay	[PMID: 23511018]
Huh-7	EC₅₀	0.55 μM Compound: 1	Antiviral activity against Hepatitis C virus infected in human Huh7.5 cells after 96 hrs by fluorescence microscopic analysis Antiviral activity against Hepatitis C virus infected in human Huh7.5 cells after 96 hrs by fluorescence microscopic analysis	[PMID: 23511018]
KM-20L2	GI₅₀	0.084 μg/mL Compound: 1b	Cytotoxicity against human KM20L2 cells Cytotoxicity against human KM20L2 cells	[PMID: 15730244]
KM-20L2	GI₅₀	0.15 μg/mL Compound: 2b	Growth inhibition of human KM20L2 cells Growth inhibition of human KM20L2 cells	[PMID: 16441059]
MCF7	GI₅₀	0.046 μg/mL Compound: 1b	Cytotoxicity against human MCF7 cells Cytotoxicity against human MCF7 cells	[PMID: 15730244]
MCF7	GI₅₀	0.093 μg/mL Compound: 2b	Growth inhibition of human MCF7 cells Growth inhibition of human MCF7 cells	[PMID: 16441059]
NCI-H460	GI₅₀	0.053 μg/mL Compound: 1b	Cytotoxicity against human NCI-H460 cells Cytotoxicity against human NCI-H460 cells	[PMID: 15730244]
NCI-H460	GI₅₀	0.11 μg/mL Compound: 2b	Growth inhibition of human NCI-H460 cells Growth inhibition of human NCI-H460 cells	[PMID: 16441059]
P388	ED₅₀	<0.01 μg/mL Compound: 2b	Growth inhibition of mouse P388 cells Growth inhibition of mouse P388 cells	[PMID: 16441059]
P388	ED₅₀	0.019 μg/mL Compound: 1b	Cytotoxicity against mouse P388 cells Cytotoxicity against mouse P388 cells	[PMID: 15730244]
SF-268	GI₅₀	0.12 μg/mL Compound: 1b	Cytotoxicity against human SF-268 cells Cytotoxicity against human SF-268 cells	[PMID: 15730244]
Vero	IC₅₀	0.042 μg/mL Compound: 2, Lycoricidine	Antiviral activity against Punta Toro virus Adames infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect by MTT assay Antiviral activity against Punta Toro virus Adames infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect by MTT assay	[PMID: 1336040]
Vero	IC₅₀	0.053 μg/mL Compound: 2, Lycoricidine	Antiviral activity against Yellow fever virus Ashibi infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect by MTT assay Antiviral activity against Yellow fever virus Ashibi infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect by MTT assay	[PMID: 1336040]
Vero	IC₅₀	0.056 μg/mL Compound: 2, Lycoricidine	Antiviral activity against Japanese encephalitis virus Nakayama infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect by MTT assay Antiviral activity against Japanese encephalitis virus Nakayama infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect by MTT assay	[PMID: 1336040]
Vero	IC₅₀	0.058 μg/mL Compound: 2, Lycoricidine	Antiviral activity against Sandfly fever sicilian virus infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect by MTT assay Antiviral activity against Sandfly fever sicilian virus infected in african green monkey Vero cells assessed as inhibition of virus-induced cytopathic effect by MTT assay	[PMID: 1336040]
Vero	IC₅₀	0.059 μg/mL Compound: 2, Lycoricidine	Antiviral activity against Dengue virus type 4 infected in african green monkey Vero cells after 6 days by plaque reduction assay Antiviral activity against Dengue virus type 4 infected in african green monkey Vero cells after 6 days by plaque reduction assay	[PMID: 1336040]
Vero	IC₅₀	0.15 μg/mL Compound: 2, Lycoricidine	Antiviral activity against Rift Valley fever virus infected in african green monkey Vero cells after 6 days by plaque reduction assay Antiviral activity against Rift Valley fever virus infected in african green monkey Vero cells after 6 days by plaque reduction assay	[PMID: 1336040]

Chemical Information

CAS No. 19622-83-4
Appearance Solid
Molecular Weight 291.26
Formula C₁₄H₁₃NO₆
Color Light yellow to light brown
SMILES

O=C1C2=CC(OCO3)=C3C=C2C4=C[C@H](O)[C@@H](O)[C@@H](O)[C@]4([H])N1
Structure Classification
- Alkaloids
- Quinoline Alkaloids
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. George R. Pettit, et al. Isolation and Structural Modification of 7-Deoxynarciclasine and 7-Deoxy-trans-Dihydronarciclasine†. J. Nat. Prod. 2006, 69.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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