8-Arm-PEG10000-DBCO 

8-Arm-PEG10000-DBCO is a eight-armed PEG derivative. The core structure of 8-Arm-PEG10000-DBCO consists of eight PEG chains, each modified at the end with a diphenylcyclooctyne (DBCO) group. 8-Arm-PEG10000-DBCO can be used for bioconjugation and drug delivery.

The structure of PEG-DBCO comprises two key parts that work synergistically:
DBCO group: A highly reactive cyclic alkyne structure capable of undergoing copper-free click chemistry (azido-alkyne cycloaddition) with molecules containing an azide group (-N3).
PEG chain: Acting as a hydrophilic spacer, it forms a hydration layer on the particle surface, reducing nonspecific adsorption and immune system recognition and clearance, thus prolonging the carrier's circulation time in vivo.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

O=C(CCC(N1CC(C=CC=C2)=C2C#CC3=C1C=CC=C3)=O)NCCOCCOCC(COCC(COCCOCCNC(CCC(N4C(C=CC=C5)=C5C#CC(C=CC=C6)=C6C4)=O)=O)(COCCOCCNC(CCC(N7C(C=CC=C8)=C8C#CC(C=CC=C9)=C9C7)=O)=O)COCC(COCCOCCNC(CCC(N%10C(C=CC=C%11)=C%11C#CC(C=CC=C%12)=C%12C%10)=O)=O)(COCCOCCNC(CCC(N%13C(C=CC=C%14)=C%14C#CC(C=CC=C%15)=C%15C%13)=O)=O)COCCOCCNC(CCC(N%16C(C=CC=C%17)=C%17C#CC(C=CC=C%18)=C%18C%16)=O)=O)(COCCOCCNC(CCC(N%19CC(C=CC=C%20)=C%20C#CC%21=C%19C=CC=C%21)=O)=O)COCCOCCNC(CCC(N%22C%23=CC=CC=C%23C#CC(C=CC=C%24)=C%24C%22)=O)=O.[n].[n].[n].[n].[n].[n].[n].[n]

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.