9,10-Dihydroacridine
Based on 1 Customer Validation
9,10-Dihydroacridine is a chain-terminating antioxidant that can inhibit lipid peroxidation by capturing peroxide free radicals (LOO•).
For research use only. We do not sell to patients.
- Purity: 99.75%
- CAS No.: 92-81-9
- Formula: C13H11N
- Molecular Weight:181.23
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| RBL-1 | IC50 |
1.6 μM
Compound: 32
|
In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cells
In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cells
|
[PMID: 2113951] |
| RBL-1 | IC50 |
1.9 μM
Compound: 32
|
In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cells
In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cells
|
[PMID: 2113951] |
| U-937 | IC50 |
0.68 μM
Compound: 4
|
Cytotoxicity in UV-irradiated human U937 cells exposed to photosensitizer for 2 hrs before irradiation for 20 mins by WST-1 assay
Cytotoxicity in UV-irradiated human U937 cells exposed to photosensitizer for 2 hrs before irradiation for 20 mins by WST-1 assay
|
[PMID: 24900465] |
Chemical Information
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CAS No. 92-81-9
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Appearance Solid
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Molecular Weight 181.23
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Formula C13H11N
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Color Light yellow to yellow
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SMILES
C12=C(NC3=C(C2)C=CC=C3)C=CC=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
DMSO : 10 mg/mL (55.18 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (269 KB)
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SDS (392 KB)
- English - EN (392 KB)
- Français - FR (392 KB)
- Deutsch - DE (392 KB)
- Norwegian - NO (392 KB)
- Español - ES (392 KB)
- Swedish - SV (392 KB)
- Italian - IT (392 KB)
- Korean - KR (392 KB)
- Portuguese - PT (392 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.5179 mL | 27.5893 mL | 55.1785 mL | 137.9463 mL |
| 5 mM | 1.1036 mL | 5.5179 mL | 11.0357 mL | 27.5893 mL | |
| 10 mM | 0.5518 mL | 2.7589 mL | 5.5179 mL | 13.7946 mL | |
| 15 mM | 0.3679 mL | 1.8393 mL | 3.6786 mL | 9.1964 mL | |
| 20 mM | 0.2759 mL | 1.3795 mL | 2.7589 mL | 6.8973 mL | |
| 25 mM | 0.2207 mL | 1.1036 mL | 2.2071 mL | 5.5179 mL | |
| 30 mM | 0.1839 mL | 0.9196 mL | 1.8393 mL | 4.5982 mL | |
| 40 mM | 0.1379 mL | 0.6897 mL | 1.3795 mL | 3.4487 mL | |
| 50 mM | 0.1104 mL | 0.5518 mL | 1.1036 mL | 2.7589 mL |