FAP Ligand 2
FAP Ligand 2, a FAPI-46 derivative, is a specific fibroblast activation protein (FAP)-targeted tracer. FAP Ligand 2 exhibits good tumor uptake and acts as a promising molecular tracer for FAP tumor imaging.
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- Formule: C43H46F2N11NaO7S
- Masse moléculaire:921.95
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
In Vitro
Chemical Information
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Masse moléculaire 921.95
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Formule C43H46F2N11NaO7S
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SMILES
O=C(C1=CC=NC2=CC=C(C=C21)N(CCCN3CCN(CC3)C([C@@H]4CCCN4C(C5=CN=C(C=C5)N/N=C/C6=C(C=CC=C6)S(=O)(O[Na])=O)=O)=O)C)NCC(N7CC(F)(C[C@]7(C#N)[H])F)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocole
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Bioluminescent/Fluorescent Imaging Xenograft
Bioluminescent and fluorescent imaging xenograft models use tumor cells engineered to express optical reporters so tumor engraftment, growth, dissemination, and treatment response can be monitored longitudinally in living animals and validated ex vivo. Bioluminescence imaging usually measures luciferase activity after substrate administration and is commonly used as a surrogate for viable reporter-expressing tumor burden, while fluorescence imaging measures reporter or probe emission and can support tumor localization, ex vivo confirmation, or complementary multimodal analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)