BMS-986163
BMS-986163 is a negative allosteric modulator of GluN2B. The proagent BMS-986163 rapidly converts to its active parent molecule BMS-986169 (Ki=4 nM, IC50=24 nM).
For research use only. We do not sell to patients.
- CAS No.: 1801151-09-6
- Formula: C23H28FN2O5P
- Molecular Weight:462.45
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
All iGluR Isoforms
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Biological Activity
Description
IC50 & Target
IC50: 24 nM (GluN2B, BMS-986169)[1]
Ki: 4 nM (GluN2B, BMS-986169)[1]
Chemical Information
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CAS No. 1801151-09-6
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Molecular Weight 462.45
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Formula C23H28FN2O5P
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SMILES
CC1=CC=C(CN2CC[C@@H](N3C[C@@H](F)[C@H](C4=CC=C(OP(O)(O)=O)C=C4)CC3)C2=O)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BMS-986163 Related Classifications
HY-107774 Related Classifications
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