1. Membrane Transporter/Ion Channel
    Neuronal Signaling
  2. iGluR
  3. BMS-986163

BMS-986163 

Cat. No.: HY-107774
Handling Instructions

BMS-986163 is a negative allosteric modulator of GluN2B. The prodrug BMS-986163 rapidly converts to its active parent molecule BMS-986169 (Ki=4 nM, IC50=24 nM).

For research use only. We do not sell to patients.

BMS-986163 Chemical Structure

BMS-986163 Chemical Structure

CAS No. : 1801151-09-6

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Description

BMS-986163 is a negative allosteric modulator of GluN2B. The prodrug BMS-986163 rapidly converts to its active parent molecule BMS-986169 (Ki=4 nM, IC50=24 nM).

IC50 & Target

IC50: 24 nM (GluN2B, BMS-986169)[1]

Ki: 4 nM (GluN2B, BMS-986169)[1]

Molecular Weight

462.45

Formula

C₂₃H₂₈FN₂O₅P

CAS No.

1801151-09-6

SMILES

CC1=CC=C(CN2CC[[email protected]@H](N3C[[email protected]@H](F)[[email protected]](C4=CC=C(OP(O)(O)=O)C=C4)CC3)C2=O)C=C1

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Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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BMS-986163
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HY-107774
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