Hemokinin 1 (mouse)
Based on 1 Customer Validation
Hemokinin 1 (mouse) is a selective agonist of neurokinin-1 receptor, with Ki of 0.175 nM and 560 nM for human NK1 receptor and human NK2 receptor, respectively.
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- Reinheit : 98.38%
- CAS. Nr.: 208041-90-1
- Formel: C61H100N22O15S
- Molecular Weight:1413.65
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Speicherung:
Stored under nitrogen, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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HY-14407A
Fosaprepitant dimeglumineNeurokinin-1 Receptor Antagonist -
HY-P1198
Hemokinin 1, humanNeurokinin Receptor Agonist -
HY-P0197
Neurokinin APeptide Neurotransmitter -
HY-P0201
Substance PNeurotransmitter -
HY-16346
NetupitantNK1 Receptor Inhibitor -
HY-101249
L-732138NK-1 Receptor Antagonist -
HY-10052
AprepitantNeurokinin 1 Receptor Antagonist -
![[Sar9,Met(O2)11]-Substance P](https://file.medchemexpress.com/product_pic/hy-p1012.gif)
HY-P1012
[Sar9,Met(O2)11]-Substance PTachykinin NK1 Receptor Agonist -
HY-14406A
L-733060 hydrochlorideNK1 Receptor Antagonist -
HY-10053
MaropitantNK1 Receptor Antagonist -
HY-14407AR
Fosaprepitant dimeglumine (Standard)Neurokinin-1 Receptor Antagonist -
HY-18006
NKP608NK-1 Receptor Antagonist
Biologische Aktivität
Beschreibung
IC50 & Target
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NK1R |
In Vitro
Hemokinin 1 (mouse) (1 nM-3 μM) produces concentration-dependent contraction of RUB averaging 66±3% (n=6) of the maximal contraction produced by KCl (80 mM). Hemokinin 1 (mouse) (10 nM-10 μM) induces a quickly-developing contractile responses of GPI, as does the tachykinin NK3 receptor selective agonist senktide or neurokinin B (NKB). Hemokinin 1 (mouse) induces full agonist responses but with a 500 fold lower potency as compared to NKB[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 208041-90-1
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Appearance Solid
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Molecular Weight 1413.65
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Formel C61H100N22O15S
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Color White to off-white
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Sequence Shortening
RSRTRQFYGLM-NH2
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Stored under nitrogen, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)
Lösungsmittel & Löslichkeit
In Vitro:
DMSO : 100 mg/mL (70.74 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (280 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 0.7074 mL | 3.5369 mL | 7.0739 mL | 17.6847 mL |
| 5 mM | 0.1415 mL | 0.7074 mL | 1.4148 mL | 3.5369 mL | |
| 10 mM | 0.0707 mL | 0.3537 mL | 0.7074 mL | 1.7685 mL | |
| 15 mM | 0.0472 mL | 0.2358 mL | 0.4716 mL | 1.1790 mL | |
| 20 mM | 0.0354 mL | 0.1768 mL | 0.3537 mL | 0.8842 mL | |
| 25 mM | 0.0283 mL | 0.1415 mL | 0.2830 mL | 0.7074 mL | |
| 30 mM | 0.0236 mL | 0.1179 mL | 0.2358 mL | 0.5895 mL | |
| 40 mM | 0.0177 mL | 0.0884 mL | 0.1768 mL | 0.4421 mL | |
| 50 mM | 0.0141 mL | 0.0707 mL | 0.1415 mL | 0.3537 mL | |
| 60 mM | 0.0118 mL | 0.0589 mL | 0.1179 mL | 0.2947 mL |
Hemokinin 1 (mouse) Related Classifications
HY-P1030 Related Classifications
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