1. Anti-infection
  2. Bacterial

MtbHU-IN-1 

Cat. No.: HY-114439
Handling Instructions

MtbHU-IN-1 is an inhibitor of Mycobacterium tuberculosis nucleoid-associated protein HU (MtbHU), with a Kd of 98 nM for binding to WT MtbHU.

For research use only. We do not sell to patients.

MtbHU-IN-1 Chemical Structure

MtbHU-IN-1 Chemical Structure

CAS No. : 59736-84-4

Size Stock
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500 mg Get quote

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Customer Review

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

MtbHU-IN-1 is an inhibitor of Mycobacterium tuberculosis nucleoid-associated protein HU (MtbHU), with a Kd of 98 nM for binding to WT MtbHU.

IC50 & Target

Kd: 98 nM (WT MtbHU )[1].

In Vitro

MtbHU-IN-1 (SD4) is an inhibitor of Mycobacterium tuberculosis nucleoid-associated protein HU (MtbHU), with Kds of 98 nM, 760 nM, 980 nM, 340 nM and 730 nM for WT and mutant MtbHUs, respectively[1].

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.1404 mL 5.7018 mL 11.4037 mL
5 mM 0.2281 mL 1.1404 mL 2.2807 mL
10 mM 0.1140 mL 0.5702 mL 1.1404 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

876.91

Formula

C₄₄H₃₆N₄O₁₂S₂

CAS No.

59736-84-4

SMILES

O=S(NC1=CC=C(C=C1)C(O)=O)(C2=CC(NC(C3=CC=C(OC)C=C3)=O)=CC=C2/C=C/C4=CC=C(NC(C5=CC=C(OC)C=C5)=O)C=C4S(NC6=CC=C(C=C6)C(O)=O)(=O)=O)=O

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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Product Name:
MtbHU-IN-1
Cat. No.:
HY-114439
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MtbHU-IN-1

Cat. No.: HY-114439