Stereospermum chelonoides DC.
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Stereospermum chelonoides DC. (1)
Sterekunthal B
Cat. No.: HY-N20619
CAS No.: 475673-78-0
- Formula: C20H18O4
- Molecular Weight: 322.35
Sterekunthal B is a naphthoquinone compound and antimalarial agent. Sterekunthal B can be isolated from plants of the Bignoniaceae family, including the root bark of Stereospermum colais. Sterekunthal B inhibits the growth of Chloroquine (HY-17589A)-sensitive Plasmodium falciparum strain PoW with an IC50 of 23.3 μg/mL. Sterekunthal B also inhibits the growth of Chloroquine-resistant Plasmodium falciparum strain Dd2 with an IC50 of 15.2 μg/mL. Sterekunthal B exhibits non-selective cytotoxicity toward endothelial cells. Sterekunthal B can be used in malaria-related research.
