Cardiovascular Disease

CB1 antagonist 1 is an antagonist of CB1 receptor, used in the research of metabolic syndrome and obesity, neuroinflammatory disorders, cognitive disorders and psychosis, gastrointestinal disorders, and cardiovascular conditions.

A81988 is a potent, competitive, non-peptidic antagonist of angiotensin AT₁ receptors.

Benzofurodil is a cardiotonic, which is used for the chronic treatment of congestive heart failure.

Thrombin inhibitor 1 is a potent thrombin inhibitor (K_i=0.66 nM, 2xaPTT=0.43 μM).

Tertatolol is a potent antagonist of beta-adrenoceptor and 5-HT receptor, with unique renal vasodilatatory effects.

5-HT3-In-1 is extracted from patent EP0748807A1, compound example 8. It shows 5-HT3 inhibition activity.

Darodipine (PY 108-068, PY-108068) is a potent calcium channel antagonist.

N-0861 racemate is the racemate of N-0861. N-0861 is a selective adenosine A1 receptor antagonist.

GP2-114 (GP-2-114) produces current-dependent cardiovascular action when administered by transdermal iontophoresis.

Saterinone is a phosphodiesterase III (PDE III) inhibitor.

LY285434 is a suitable angiotensin II receptor antagonist.

Bunaftide (Bunaftine; Bunaphtide; Meregon) is an antiarrhythmic agent.

DU-717 is an antihypertensive agent.

Epanolol (Visacor; ICI141292) is a potent β-adrenoceptor partial agonist with a greater affinity for β1- than β2-adrenoceptors.

5-HT2 antagonist 1 is a potent antagonist of 5-HT2 receptor, with weak α1 adrenoceptor blocking activity.

Anti-Heart Failure Agent 1 an orally available compound suitable for the treatment of heart failure without inducing nausea, vomiting and restlessness.