1. Alkaloid

Sauristolactam (Synonyms: Saurolactam)

Cat. No.: HY-118482
Handling Instructions

Sauristolactam, a natural aristolactam isolated from aerial portions of Saururus chinensis, has significant neuroprotective activity against glutamate-induced toxicity in primary cultured rat cortical cells. Sauristolactam also inhibits the receptor activator of nuclear factor-κB ligand (RANKL)-induced osteoclastogenesis and has the potential to inhibit osteoclast differentiation.

For research use only. We do not sell to patients.

Sauristolactam Chemical Structure

Sauristolactam Chemical Structure

CAS No. : 128533-02-8

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  • Biological Activity

  • Technical Information

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  • References

Description

Sauristolactam, a natural aristolactam isolated from aerial portions of Saururus chinensis, has significant neuroprotective activity against glutamate-induced toxicity in primary cultured rat cortical cells[1]. Sauristolactam also inhibits the receptor activator of nuclear factor-κB ligand (RANKL)-induced osteoclastogenesis and has the potential to inhibit osteoclast differentiation[2].

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.5805 mL 17.9025 mL 35.8051 mL
5 mM 0.7161 mL 3.5805 mL 7.1610 mL
10 mM 0.3581 mL 1.7903 mL 3.5805 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

279.29

Formula

C₁₇H₁₃NO₃

CAS No.

128533-02-8

SMILES

O=C1N(C2=C3C1=CC(O)=C(C3=C4C(C=CC=C4)=C2)OC)C

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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Product Name:
Sauristolactam
Cat. No.:
HY-118482
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Sauristolactam

Cat. No.: HY-118482