1. Signaling Pathways
  2. GPCR/G Protein
    Neuronal Signaling
  3. 5-HT Receptor
  4. 5-HT7 Receptor Isoform
  5. 5-HT7 Receptor Modulator

5-HT7 Receptor Modulator

5-HT7 Receptor Modulators (5):

Cat. No. Product Name Effect Purity
  • HY-14539
    Clozapine
    Modulator 99.99%
    Clozapine (HF 1854) is an antipsychotic used for the research of schizophrenia.
  • HY-B0032A
    Lurasidone
    Modulator 99.90%
    Lurasidone (SM-13496) is an antagonist of both dopamine D2 and 5-HT7 with IC50s of 1.68 and 0.495 nM, respectively.
  • HY-N0049
    Nuciferine
    Modulator 99.46%
    Nuciferine is an antagonist at 5-HT2A (IC50=478 nM), 5-HT2C (IC50=131 nM), and 5-HT2B (IC50=1 μM), an inverse agonist at 5-HT7 (IC50=150 nM), a partial agonist at D2 (EC50=64 nM), D5 (EC50=2.6 μM) and 5-HT6 (EC50=700 nM), an agonist at 5-HT1A (EC50=3.2 μM) and D4 (EC50=2 μM) receptor.
  • HY-B0032
    Lurasidone Hydrochloride
    Modulator 99.96%
    Lurasidone (Hydrochloride) (SM-13496 (Hydrochloride)) is an antagonist of both dopamine D2 and 5-HT7 with IC50s of 1.68 and 0.495 nM, respectively.
  • HY-109112
    Brilaroxazine
    Modulator 98.29%
    Brilaroxazine (RP5603) is a potent and orally active multimodal dopamine (DA)/serotonin (5-HT) modulator.