Angiotensin Receptor
Angiotensin receptors are a class of G protein-coupled receptors with angiotensin II as their ligands. They are important in the renin-angiotensin system: they are responsible for the signal transduction of the vasoconstricting stimulus of the main effector hormone, angiotensin II. The AT1 and AT2 receptors have a similar affinity for angiotensin II, which is their main ligand. The AT1 receptor is the best elucidated angiotensin receptor. AT2 receptors are more plentiful in the fetus and neonate. Other poorly characterized subtypes include the AT3 and AT4 receptors.
Angiotensin Receptor Isoform Specific Products
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Angiotensin Receptor Inhibitors
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Angiotensin Receptor Agonists
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Angiotensin Receptor Antagonists
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Angiotensin Receptor Activators
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Angiotensin Receptor Modulators
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Angiotensin Receptor Chemicals
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Angiotensin Receptor Ligands
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Angiotensin Receptor Related Products (300)
Related Products (300)
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Antibodies (7)
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Angiotensin Receptor Isoform Comparison
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Candesartan Cilexetil-d11
0 ImagesCat. No.: HY-W707384CAS No.: 1261393-19-4Synonyms: TCV-116-d11Candesartan Cilexetil-d11 (TCV-116-d11) is deuterium labeled Candesartan Cilexetil. Candesartan Cilexetil (TCV-116) is an angiotensin II receptor inhibitor. Candesartan Cilexetil ameliorates the pulmonary fibrosis and has antiviral and skin wound healing effect. Candesartan Cilexetil can be used for the research of high blood pressure.
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ZD-6888 hydrochloride
0 ImagesCat. No.: HY-19156ACAS No.: 138620-17-4Synonyms: ICI-D 6888 hydrochlorideZD-6888 hydrochloride (ICI-D 6888 hydrochloride) is an antagonist for angiotensin II, which competitively inhibits the angiotensin II-mediated release of renin, affects the renal structure and function.
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Valsartan methyl ester (Standard)
0 ImagesSynonyms: CGP 48933 methyl ester (Standard)Valsartan (CGP 48933) methyl ester (Standard) is the analytical standard of Valsartan methyl ester (HY-W414915). This product is intended for research and analytical applications. Valsartan methyl ester is the methyl ester derivative of Valsartan (HY-18204). Valsartan is a selective angiotensin II type 1 (AT1) receptor blocker (ARB) with potent antihypertensive and cardioprotective effects. Valsartan competitively binds to AT1 receptors, inhibiting the binding of angiotensin II to AT1 receptors, thereby blocking angiotensin II-mediated vasoconstriction, sodium retention, and myocardial hypertrophy signaling pathways. Valsartan reduces systolic blood pressure in L-NAME-induced hypertensive rats. Valsartan can be used for the study and treatment of arterial hypertension, hypertensive heart disease, and heart failure.
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Losartan (Standard)
0 ImagesSynonyms: DuP-753 (Standard)Losartan (Standard) is the analytical standard of Losartan. This product is intended for research and analytical applications. Losartan is an angiotensin II receptor antagonist, competing with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM.
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1-Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone
![1-Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone](https://file.medchemexpress.com/product_pic/hy-n9520.gif "Click to View 1-Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone Product Detail")
0 ImagesCat. No.: HY-N9520CAS No.: 120693-52-9Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone9 is an antagonist of angiotensin II receptor (IC50=48.2 μM). Methyl-2-[(6Z,9Z)-6,9-pentadecadienyl]-4(1H)-quinolone9 is a quinolone alkaloid from Evodia rutaecarpa.
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L 158338
0 ImagesCat. No.: HY-117627CAS No.: 133240-38-7L 158338 is an angiotensin II receptor antagonist. L 158338 alleviates acidosis and increases coronary blood flow during the ischemic period and increases coronary blood flow during the reperfusion period. L 158338 can be used to study myocardial injury during ischemia and reperfusion.
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Irbesartan-d7 hydrochloride
0 ImagesCat. No.: HY-B0202ASSynonyms: SR-47436-d7 hydrochloride; BMS-186295-d7 hydrochlorideIrbesartan-d7 hydrochloride is deuterated labeled Irbesartan hydrochloride (HY-B0202A). Irbesartan (SR-47436) hydrochloride is an orally active Ang II type 1 (AT1) receptor blocker (ARB). Irbesartan hydrochloride can relax the blood vessels, low blood pressure and increase the supply of blood and oxygen to the heart. Irbesartan hydrochloride can be used for the research of high blood pressure, heart failure, and diabetic kidney disease.
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Candesartan methyl ester (Standard)
0 ImagesCat. No.: HY-W098792RCAS No.: 139481-69-9
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Azilsartan medoxomil monopotassium (Standard)
0 ImagesCat. No.: HY-17458RCAS No.: 863031-24-7Synonyms: Azilsartan kamedoxomil (Standard); TAK 491 monopotassium (Standard)Azilsartan medoxomil monopotassium (Standard) is the analytical standard of Azilsartan medoxomil monopotassium (HY-17458V). This product is intended for research and analytical applications. Azilsartan medoxomil (TAK 491) monopotassium, a prodrug form of Azilsartan (HY-14914), is an orally active angiotensin II receptor type 1 antagonist. Azilsartan medoxomil monopotassium can be used for the study of essential hypertension.
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Elisartan
0 ImagesCat. No.: HY-19214CAS No.: 149968-26-3Synonyms: HN 65021Elisartan is an orally active non-peptide pro-agent of angiotensin II AT1 receptor antagonist HN-12206, and shows anti-hypertension activities.
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CGP48369
0 ImagesCat. No.: HY-101706CAS No.: 135689-23-5CGP48369 is a nonpeptidic angiotensin II receptor antagonist, used for anti-hypertensive research.
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L-159282
0 ImagesCat. No.: HY-19191CAS No.: 157263-00-8Synonyms: MK 996L-159282 is a highly potent, orally active, nonpeptide angiotensin II receptor antagonist, with anti-hypertensive activity.
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L162389
0 ImagesL162389 is a potent antagonist of angiotensin AT1 receptor with Ki of 28 nM.
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A-81282
0 ImagesCat. No.: HY-101823ACAS No.: 141872-46-0Synonyms: Abbott 81282A-81282 (Abbott 81282) is an antagonist of angiotensin II's AT1 receptor, with a pA2 value of 9.64 at the AT1 receptor in rabbit aorta. A-81282 also demonstrates significant inhibitory action on the binding of [125i]_Sar1_lle8_Angiotensin_ll to rat liver membranes, with a pKI value of 8.505. A-81282 has antihypertensive activity and can effectively lower blood pressure in renal artery-ligated rats.
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PD 123319 ditrifluoroacetate (Standard)
0 ImagesCat. No.: HY-10259ARCAS No.: 136676-91-0PD 123319 ditrifluoroacetate (Standard) is the analytical standard of PD 123319 ditrifluoroacetate (HY-10259A). This product is intended for research and analytical applications. PD 123319 ditrifluoroacetate is a potent, selective AT2 angiotensin II receptor antagonist with IC50 of 34 nM.
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Nepitrin (Standard)
0 ImagesNepitrin (Standard) (Nepetin-7-glucoside (Standard)) is the analytical standard of Nepitrin (HY-N5010). This product is intended for research and analytical applications. Nepitrin (Nepetin-7-glucoside) is an orally active bradykinin and angiotensin antagonist isolated from Scrophularia striata. Nepitrin antagonizes the spasmogenic effects of Bradykinin and Angiotensin, thereby inhibiting inflammatory mediator pathways. Nepitrin is applicable to arthritis-related research.
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ZD 7155hydrochloride (Standard)
0 ImagesCat. No.: HY-102093RCAS No.: 146709-78-6ZD 7155(hydrochloride) (Standard) is the analytical standard of ZD 7155(hydrochloride). This product is intended for research and analytical applications. ZD 7155 hydrochloride is an angiotensin II receptor type 1 (AT1 receptor) antagonist.
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Olmesartan lactone impurity (Standard)
0 ImagesCat. No.: HY-131276RCAS No.: 849206-43-5Olmesartan lactone impurity (Standard) is the analytical standard of Olmesartan lactone impurity. This product is intended for research and analytical applications. Olmesartan lactone impurity is a cyclic ester impurity of Olmesartan. Olmesartan is an angiotensin II receptor (AT1R) antagonist and has the potential for high blood pressure study.
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Olmesartan impurity
0 ImagesCat. No.: HY-133775CAS No.: 154709-18-9Olmesartan impurity is an Olmesartan impurity. Olmesartan (RNH-6270) is an angiotensin II receptor (AT1R) antagonist has the potential for high blood pressure study.
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GA 0113
0 ImagesCat. No.: HY-167886CAS No.: 200639-61-8
