Angiotensin Receptor
Angiotensin receptors are a class of G protein-coupled receptors with angiotensin II as their ligands. They are important in the renin-angiotensin system: they are responsible for the signal transduction of the vasoconstricting stimulus of the main effector hormone, angiotensin II. The AT1 and AT2 receptors have a similar affinity for angiotensin II, which is their main ligand. The AT1 receptor is the best elucidated angiotensin receptor. AT2 receptors are more plentiful in the fetus and neonate. Other poorly characterized subtypes include the AT3 and AT4 receptors.
Angiotensin Receptor Isoform Specific Products
All Product Categories
-
Angiotensin Receptor Inhibitors
(34)
View all products
-
Angiotensin Receptor Agonists
(23)
View all products
-
Angiotensin Receptor Antagonists
(163)
View all products
-
Angiotensin Receptor Activators
(33)
View all products
-
Angiotensin Receptor Modulators
(3)
View all products
-
Angiotensin Receptor Chemicals
(2)
View all products
-
Angiotensin Receptor Ligands
(2)
View all products
-
Angiotensin Receptor Related Products (298)
Related Products (298)
-
Antibodies (7)
-
Angiotensin Receptor Isoform Comparison
-
GA-0056
0 ImagesCat. No.: HY-19207CAS No.: 153465-66-8GA-0056 is an angiotensin II receptor blocker. GA-0056 can be used in the research of heart disease.
-
C-Type Natriuretic Peptide (1-53), human
0 ImagesCat. No.: HY-P1815CAS No.: 141294-77-1C-Type Natriuretic Peptide (1-53), human is the 1-53 fragment of C-Type Natriuretic Peptide. C-Type Natriuretic Peptide is natriuretic peptide family peptide that is involved in the maintenance of electrolyte-fluid balance and vascular tone.
-
L-163958
0 ImagesCat. No.: HY-114284CAS No.: 168473-51-6L-163958 is an efficient, orally active, balanced angiotensin II receptor (AII receptor) antagonist. L-163958 has balanced high affinity for AT1 and AT2, with its IC50 values being 0.16, 0.12, 0.50, and 0.64 nM in rabbit aorta (AT1), rat midbrain (AT2), human adrenal gland (AT1), and human adrenal gland (AT2), respectively. L-163958 has a strong inhibitory effect on the pressor activity in rats. L-163958 can be used for the study of hypertension and related cardiovascular diseases.
-
[Sar1,Thr8]-Angiotensin II
![[Sar1,Thr8]-Angiotensin II](https://file.medchemexpress.com/product_pic/hy-p10640.gif "Click to View [Sar1,Thr8]-Angiotensin II Product Detail")
0 ImagesCat. No.: HY-P10640CAS No.: 53632-49-8[Sar1,Thr8]-Angiotensin II is a potent angiotensin II antagonist. [Sar1,Thr8]-Angiotensin II does not alter cardiac performance. [Sar1,Thr8]-Angiotensin II might be safe for patients with cardiac disease.
-
Tranilast (Standard)
0 ImagesSynonyms: MK-341 (Standard); SB 252218 (Standard)Tranilast (Standard) is the analytical standard of Tranilast. This product is intended for research and analytical applications. Tranilast (MK-341) acts as an anti-atopic agent. Tranilast suppresses production of prostaglandin D2 (PGD2, IC50= 0.1 mM). Tranilast sodium exhibits anti-inflammatory and immunomodulatory effects. Tranilast sodium antagonizes angiotensin II and inhibits its biological effects in vascular smooth muscle cells.
-
Evazarsen sodium scrambled negative control
0 ImagesCat. No.: HY-147267CEvazarsen sodium scrambled negative control is the sequence scrambled negative control of Evazarsen sodium.
-
Fonsartan
0 ImagesCat. No.: HY-19224CAS No.: 153235-15-5Synonyms: HR 720Fonsartan (HR720) is an AT1 receptor antagonist. Fonsartan can be used for the study of myocardial infarction (MI).
-
Angiotensin I/II (1-6)
0 ImagesCat. No.: HY-P1829CAS No.: 47896-63-9Angiotensin I/II 1-6 contains the amino acids 1-6 and is converted from Angiotensin I/II peptide. The precursor angiotensinogen is cleaved by renin to form angiotensin I. Angiotensin I ishydrolyzed by angiotensin-converting enzyme (ACE) to form the biologically active angiotensin II. Angiotensin II has been investigated for the treatment, basic science, and diagnostic of Hypertension, Renin Angiotensin System, and Idiopathic Membranous Nephropathy.
-
Angiotensin II/BSA
0 ImagesCat. No.: HY-161530Angiotensin II/BSA is an antigen-adjuvant conjugate formed by the coupling of Angiotensin II with bovine serum albumin (BSA). By coupling the antigen with a protein adjuvant, the production of antigen-specific antibodies in vaccine models can be enhanced. The conjugate does not affect protein folding or disrupt major epitopes, and it can enhance cross-presentation and the generation of antigen-specific T cells.
-
Saprisartan
0 ImagesCat. No.: HY-A0229CAS No.: 146623-69-0Synonyms: GR 138950Saprisartan (GR 138950) is a selective, long-acting AT1 receptor antagonist with low receptor dissociation kinetics.
-
PD 121981
0 ImagesCat. No.: HY-105453CAS No.: 114785-18-1Synonyms: WL 19PD 121981 is a angiotensin II receptor antagonist. PD 121981 can be used for the research of cardiovascular disease.
-
AZ11657312
0 ImagesCat. No.: HY-122282CAS No.: 804561-22-6AZ11657312 is a P2X7 receptor antagonist with activity to restore stress natriuresis. AZ11657312 significantly increased renal medullary perfusion, only in mice treated with angiotensin II. AZ11657312 improves tissue oxygenation by blocking P2X7R, especially in areas of the kidney that are underoxygenated. Administration of AZ11657312 increased sodium excretion up to sixfold while normalizing blood pressure.
-
Enoltasosartan
0 ImagesCat. No.: HY-160292CAS No.: 159237-67-9Enoltasosartan is an angiotensin II (AngII) receptor blocker.
-
Telmisartan-13C,d3
0 ImagesCat. No.: HY-13955S2CAS No.: 1261396-33-1Synonyms: BIBR 277-13C,d3Telmisartan-13C,d3 is the 13C- and deuterium labeled Telmisartan. Telmisartan is a potent, long lasting antagonist of angiotensin II type 1 receptor (AT1), selectively inhibiting the binding of 125I-AngII to AT1 receptors with IC50 of 9.2 nM.
-
KR31173
0 ImagesCat. No.: HY-165425CAS No.: 260554-07-2KR31173 is an AT1 antagonist with an IC50 of 3.27 nM. KR31173 can be used as a positron emission tomography (PET) tracer after being labeled with 11C isotope. KR31173 shows promising biodistribution and pharmacological properties in mice. KR31173 selectively binds to organs known to contain a high density of AT1 angiotensin receptors in CD-1 mice.
-
L-163017
0 ImagesCat. No.: HY-114283CAS No.: 169281-98-5L-163017 is a potent, orally active and nonpeptide angiotensin II receptor (AT) antagonist. L-163017 can inhibit prevent the pressor response to angiotensin II and reduce blood pressure. L-163017 can be used for the research of cardiovascular disease, such as hypertension.
-
5-O-beta-D-Glucopyranosylmyricanol
0 ImagesCat. No.: HY-N10860CAS No.: 90052-02-15-O-beta-D-Glucopyranosylmyricanol is a diarylheptane compound isolated from Myrica esculenta that has a weak inhibitory effect on angiotensin-converting enzyme (ACE).
-
EXP-7711
0 ImagesEXP-7711 is a non peptide angiotensin II (Ang II) AT1 receptor antagonist. EXP-7711’s affinity for wild-type AT1 receptor (Ki =180 nM) is lower than peptide antagonists, but higher than losartan (Ki = 12 nM). EXP-7711 can be used for research on cardiovascular conditions.
