260554-07-2
260554-07-2
Chemical Structure
KR31173
- CAS No.: 260554-07-2
- Formula:C31H30N8O2
- Molecular Weight:546.62
InChIKey: KTIHPEHEYAUWHK-UHFFFAOYSA-N
SMILES: [O-][N+]1=CC=CC=C1C2=C(COC)N=C(N(CC3=CC=C(C4=CC=CC=C4C5=NN=NN5)C=C3)C(CCCC)=N6)C6=C2
Biological Activity: KR31173 is an AT1 antagonist with an IC50 of 3.27 nM. KR31173 can be used as a positron emission tomography (PET) tracer after being labeled with 11C isotope. KR31173 shows promising biodistribution and pharmacological properties in mice. KR31173 selectively binds to organs known to contain a high density of AT1 angiotensin receptors in CD-1 mice[1].
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KR31173 | KR31173 is an AT1 antagonist with an IC50 of 3.27 nM. KR31173 can be used as a positron emission tomography (PET) tracer after being labeled with 11C isotope. KR31173 shows promising biodistribution and pharmacological properties in mice. KR31173 selectively binds to organs known to contain a high density of AT1 angiotensin receptors in CD-1 mice. | |||||||||||||||||||||
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References
Keywords
