L-163958
L-163958 is an efficient, orally active, balanced angiotensin II receptor (AII receptor) antagonist. L-163958 has balanced high affinity for AT1 and AT2, with its IC50 values being 0.16, 0.12, 0.50, and 0.64 nM in rabbit aorta (AT1), rat midbrain (AT2), human adrenal gland (AT1), and human adrenal gland (AT2), respectively. L-163958 has a strong inhibitory effect on the pressor activity in rats. L-163958 can be used for the study of hypertension and related cardiovascular diseases.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 168473-51-6
- Formel: C33H37BrFN5O6S
- Molecular Weight:730.64
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biologische Aktivität
-
Chemical Information
- Reinheit & Dokumentation
- Verweise
-
Help & FAQs
Alle Angiotensin Receptor Isoform-spezifische Produkte anzeigen
More
Biologische Aktivität
|
AT1 Receptor 0.16 nM (IC50) |
AT2 Receptor 0.12 nM (IC50) |
Chemical Information
-
CAS. Nr. 168473-51-6
-
Molecular Weight 730.64
-
Formel C33H37BrFN5O6S
-
SMILES
O=C(OC(C)(C)C)NS(=O)(C1=CC=CC=C1C2=CC=C(CN3C(CC)=NN(C4=CC(NC(CCCC)=O)=CC=C4Br)C3=O)C(F)=C2)=O
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
L-163958 Related Classifications
HY-114284 Related Classifications
Powered by Bioz