153235-15-5
Chemical Structure
Fonsartan
Synonym(s): HR 720
- CAS No.: 153235-15-5
- Formula:C26H30K2N4O5S2
- Molecular Weight:620.87
IUPAC Name: 2-butyl-4-(methylthio)-1-((2'-(N-(propylcarbamoyl)sulfamoyl)-[1,1'-biphenyl]-4-yl)methyl)-1H-imidazole-5-carboxylic acid, dipotassium salt
InChIKey: LSQWBTMKGNRLEV-UHFFFAOYSA-L
SMILES: O=C(C1=C(SC)N=C(CCCC)N1CC2=CC=C(C3=C(S(=O)(N([K])C(NCCC)=O)=O)C=CC=C3)C=C2)O[K]
Biological Activity: Fonsartan (HR720) is an AT1 receptor antagonist. Fonsartan can be used for the study of myocardial infarction (MI)[1][2].
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Fonsartan | Fonsartan (HR720) is an AT1 receptor antagonist. Fonsartan can be used for the study of myocardial infarction (MI). | |||||||||||||||||||||
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- [1]. Xia QG, et al. Significance of timing of angiotensin AT1 receptor blockade in rats with myocardial infarction-induced heart failure. Cardiovasc Res. 2001 Jan;49(1):110-7. [Content Brief]
- [2]. Jin D, et al. Pharmacological profiles of a novel non-peptide angiotensin II type I receptor antagonist HR720 in vitro and in vivo. Jpn J Pharmacol. 1997 Nov;75(3):259-66. [Content Brief]
Keywords