1. Signaling Pathways
  2. Anti-infection
  3. Bacterial

Bacterial

Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-10581AS
    Gatifloxacin-d3 hydrochloride
    Inhibitor
    Gatifloxacin-d3 (hydrochloride) is the deuterium labeled Gatifloxacin (hydrochloride). Gatifloxacin hydrochloride (AM-1155; BMS-206584; PD135432) is a potent fluoroquinolone antibiotic with broad-spectrum antibacterial activity. Gatifloxacin hydrochloride inhibits bacterial type II topoisomerases (IC50=13.8 μg/ml for S. aureus topoisomerase IV) and E. coli DNA gyrase (IC50 = 0.109 μg/ml). Gatifloxacin hydrochloride can be used to treat bacterial conjunctivitis in vivo.
    Gatifloxacin-d<sub>3</sub> hydrochloride
  • HY-149346
    Mtb-IN-2
    Inhibitor
    Mtb-IN-2 (compound 10c) is an antimicrobial agent against Mycobacterium tuberculosis (Mtb), without cytotoxicity. Mtb-IN-2 significantly decreases colony-forming units (CFU) in spleen of murine tuberculosis models, and distinguishes both drug-sensitive and drug-resistant Mtb H37Rv strains. Mtb-IN-2 affects methionine metabolism but not folate pathway directly.
    Mtb-IN-2
  • HY-N6949R
    Juglone (Standard)
    Inhibitor
    Juglone (Standard) is the analytical standard of Juglone. This product is intended for research and analytical applications. Juglone (5-hydroxy-1,4-naphthalenedione) is a yellow dye that can be extracted from Juglans regia. Juglone induces apoptosis through the mitochondrial pathway. Juglone has antibacterial and antitumor activity .
    Juglone (Standard)
  • HY-N12524
    Cyclo(prolyltyrosyl)
    Inhibitor
    Cyclo(prolyltyrosyl) is a natural compound that can be found in various microorganisms and marine sponges. Cyclo(prolyltyrosyl) has antibacterial, phytotoxic and cytotoxic properties.
    Cyclo(prolyltyrosyl)
  • HY-N0199
    Albaspidin AA
    Inhibitor
    Albaspidin AA displays strong antibacterial activity against the vegetative form of Paenibacillus larvae (P. larvae) (MIC=220 μM).
    Albaspidin AA
  • HY-105099R
    Rifalazil (Standard)
    Inhibitor
    Rifalazil (Standard) is the analytical standard of Rifalazil. This product is intended for research and analytical applications. Rifalazil (KRM-1648; ABI-1648), a rifamycin derivative, inhibits the bacterial DNA-dependent RNA polymerase and kills bacterial cells by blocking off the β-subunit in RNA polymerase[1]. Rifalazil (KRM-1648; ABI-1648) is an antibiotic, exhibits high potency against mycobacteria, gram-positive bacteria, Helicobacter pylori, C. pneumoniae and C. trachomatis with MIC values from 0.00025 to 0.0025 μg/ml[3]. Rifalazil (KRM-1648; ABI-1648) has the potential for the treatment of Chlamydia infection, Clostridium difficile associated diarrhea (CDAD), and tuberculosis (TB)[2].
    Rifalazil (Standard)
  • HY-N18007
    3-Hydroxyglabrol
    Inhibitor
    3-Hydroxyglabrol is an Antibacterial agent. 3-Hydroxyglabrol can be isolated from Glycyrrhiza glabra L. var. typica. 3-Hydroxyglabrol inhibits the growth of Staphylococcus aureus (ATCC 13709) and Mycobacterium smegmatis (ATCC 607), with a MIC of 6.25 mcg/mL. 3-Hydroxyglabrol can be used for the research of Staphylococcus aureus infection, Mycobacterium smegmatis infection.
    3-Hydroxyglabrol
  • HY-117074
    BMS-247243
    Inhibitor
    BMS-247243 is a β-lactam antibiotic against methicillin (HY-121544)-resistant Staphylococcus aureus.
    BMS-247243
  • HY-N12258
    Aranciamycin A
    Inhibitor
    Aranciamycin A is an anthracyclic antibiotic and can be isolated from Streptomyces. Aranciamycin A shows antibacterial activity against M. bovis and B. subtilis with the MIC values of 30 and 7.5 µM, respectively.
    Aranciamycin A
  • HY-135535
    Sclerotioramine
    Inhibitor
    Sclerotioramine (Compound 1), a red pigment, is an antioxidant compound. Sclerotioramine can be isolated from the endolichenic fungus Penicillium sp.-strain 1322P. Sclerotioramine has potent antibacterial activity with MICs of 3.125, 3.125 and 6.25 μg/mL for Bacillus subtilis, Bacillus megaterium and Shigella dysentery, respectively. Sclerotioramine also has significant antifungal activity against Pestalotiopsis theae, Cochliobolus miyabeanus and Exserohilum turcicum.
    Sclerotioramine
  • HY-149534
    DNA Gyrase-IN-9
    Inhibitor
    DNA Gyrase-IN-9 (compound 4j) is an antibacterial agent that targets DNA gyrase. The MIC to inhibit Gram bacteria is 0.5-2 μg/mL, and the MBC to kill Gram bacteria is 2-8 μg/mL. DNA Gyrase-IN-9 inhibits DNA gyrase in Staphylococcus aureus with IC50=6.29 μg/mL.
    DNA Gyrase-IN-9
  • HY-B1584R
    Captan (Standard)
    Inhibitor
    Captan (Standard) is the analytical standard of Captan. This product is intended for research and analytical applications. Captan is a common agricultural fungicide used to control Botrytis, Fusarium, Fusicoccum, Pythium. Captan enhances denitrifying and total culturable bacteria.
    Captan (Standard)
  • HY-P11139
    Lactocin 705β
    Inhibitor
    Lactocin 705β (Lac705β) is a peptide segment that can form class IIb bacteriocins Lactocin 705 with Lac705α (HY-P11138) . Lactocin 705β has no antibacterial activity when used alone. Lactocin 705β can be used for research on bacterial infections.
    Lactocin 705β
  • HY-114604
    Propioxatin B
    Inhibitor
    Propioxatin B is a tricyclic sesquiterpenoid compound isolated from the root of vetiver grass. It has anti-tuberculosis activity and inhibitory effects on a variety of drug-resistant mutants of Mycobacterium tuberculosis. In computer simulation docking studies, it showed binding affinity with bacterial DNA gyrase and has a certain safety in vivo.
    Propioxatin B
  • HY-W150903
    N-Heptyl 4-hydroxybenzoate
    Inhibitor 99.60%
    N-Heptyl 4-hydroxybenzoate (p-Oxybenzoesaureheptylester) is an antimicrobial agent that inhibits S. aureus with MIC of 12.5 μg/mL. N-Heptyl 4-hydroxybenzoate also against plant pathogenic fungi, such as Alternaria brassicicola, F. solani, C. dematium and C. acutatum.
    N-Heptyl 4-hydroxybenzoate
  • HY-N1637
    1-Methyl-2-pentyl-4(1H)-quinolinone
    99.94%
    1-Methyl-2-pentyl-4(1H)-quinolinone, a quinolone alkaloid isolated from the fruits of Evodia Rutaecarpa, possesses antibacterial and cytotoxic activities for cancer cells.
    1-Methyl-2-pentyl-4(1H)-quinolinone
  • HY-B0421AR
    Mycophenolic acid sodium (Standard)
    Inhibitor
    Mycophenolic acid (sodium) (Standard) is the analytical standard of Mycophenolic acid (sodium). This product is intended for research and analytical applications. Mycophenolic acid sodium is a potent uncompetitive inosine monophosphate dehydrogenase (IMPDH) inhibitor with an EC50 of 0.24 μM. Mycophenolic acid sodium demonstrates antiviral effects against a wide range of RNA viruses including influenza. Mycophenolic acid sodium is an immunosuppressive agent. Antiangiogenic and antitumor effects.
    Mycophenolic acid sodium (Standard)
  • HY-17466A
    Sancycline hydrochloride
    Sancycline (6-Demethyl-6-deoxytetracycline) hydrochloride acts by reversibly binding to the 30 S ribosomal subunit and inhibiting protein translation by blocking entry of aminoacyl-tRNA into the ribosome a site similar to tetracycline (HY-A0107). Sancycline hydrochloride, four linearly fused six-membered rings with four stereocenters, is a rare semi-synthetic tetracycline (HY-A0107) prepared by hydrogenolysis of the chloro and benzylic hydroxy moieties of Declomycin.
    Sancycline hydrochloride
  • HY-D3390
    sCy5DA
    sCy5DA is a is a fluorescent D-amino acid. sCy5DA incorporates into bacterial peptidoglycan layers and cross-links via transpeptidase action, replacing peptidoglycan stem peptide D-amino acids. sCy5DA labels live bacterial cell walls, nascent peptidoglycan biosynthesis sites, and diverse bacterial species including Gram-negative, Gram-positive, and mycobacteria (Ex/Em = 646/665 nm).
    sCy5DA
  • HY-111320
    Chrysomycin B
    Inhibitor
    Chrysomycin B is an antibiotic isolated from a strain of Streptomyces. Chrysomycin B causes DNA damage in the human lung adenocarcinoma A549 cell line and inhibits topoisomerase II. Chrysomycin B suppresses the growth of transplantable tumors in mice.
    Chrysomycin B
Cat. No. Product Name / Synonyms Application Reactivity