2. Signaling Pathways
  3. Neuronal Signaling
  4. CaMK
  5. CaMK III/eEF-2K Isoform
  6. CaMK III/eEF-2K Degrader

CaMK III/eEF-2K Degrader

CaMK III/eEF-2K Degrader (1):

Cat. No. Product Name Effect Purity
  • HY-181506
    TYMJ-01
    		Degrader
    TYMJ-01 is a fluorescent probe and eEF2K degrader. TYMJ-01 induces dose-dependent and specific degradation of eEF2K via the ubiquitin-proteasome pathway, with a DC50 of 82 nM. TYMJ-01 inhibits the proliferation, migration and invasion of triple-negative breast cancer cells. TYMJ-01 enables dynamic fluorescent imaging of eEF2K degradation in triple-negative breast cancer cells; it enhances the anti-tumor activity of Paclitaxel (HY-B0015). TYMJ-01 can be used for the research of triple-negative breast cancer.