Drug Derivative
Drug derivative
Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.
References:
- [1]. Vardanyan RS, et al. Fentanyl-related compounds and derivatives: current status and future prospects for pharmaceutical applications. Future Med Chem. 2014 Mar;6(4):385-412.x
- [2]. Ghosh AK, et al. Urea Derivatives in Modern Drug Discovery and Medicinal Chemistry. J Med Chem. 2020 Mar 26;63(6):2751-2788.x
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Drug Derivative Related Products (3989)
Related Products (3989)
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Nujiangefolin A
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Chlorcyclamide
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Stelleranoid B
0 ImagesCat. No.: HY-N17201CAS No.: 2957870-90-3Stelleranoid B is a natural flavonoid.
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Trollisin I
0 ImagesCat. No.: HY-N21544CAS No.: 911063-04-2Trollisin I is a flavonoid C-glycoside present in the flowers of Trollius chinensis, and it exhibits no significant activity against influenza A and influenza B viruses.
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Kelletinin A
0 ImagesCat. No.: HY-125054CAS No.: 112727-22-7Synonyms: BuccinulinKelletinin A is an active compound.
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Org-9768
0 ImagesCat. No.: HY-W223348CAS No.: 759424-59-4Org-9768 (Compound (2-methyl-2,3-dihydro-1H-inden-2-yl)methanamine) is a drug intermediate for synthesizing the mitochondrial permeability transition pore (mPTP) inhibitor. Org-9768 can be used for the researches of neurological and cardiovascular disease, such as Parkinson's disease.
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AF 698
0 ImagesCat. No.: HY-129406CAS No.: 82958-11-0AF 698 is a phthalate derivative of Apovincamine (HY-135743) that can be used as a peripheral vasodilator with selective vasomotor effects on cerebral microvascular circulation. AF 698 has better vasodilator effect than Vincamine (HY-B1021), but there is no significant difference in the protective effect of the two drugs against hypobaric hypoxia-induced lethality in mice.
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YM-08050
0 ImagesCat. No.: HY-123332CAS No.: 73328-60-6
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TH301
0 ImagesCat. No.: HY-134192CAS No.: 450338-32-6TH301 is a Phenylpyrazole derivative. TH301 selectively stabilize CRY2. TH301 dose-dependently prolongs circadian period.
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CB 966
0 ImagesCat. No.: HY-117638CAS No.: 128312-71-0CB 966 a Vitamin D3 (HY-15398) analogue, is an immunosuppressant. CB 966 delays rejection of allogeneic skin grafts in mice. CB 966 moderately increases serum calcium levels. CB 966 can be used for the research of allogeneic skin graft rejection.
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cis-LY393053
0 ImagesCat. No.: HY-123253CAS No.: 394735-81-0cis-LY393053 is an active compound.
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Lycorine methiodide
0 ImagesCat. No.: HY-137052CAS No.: 15069-99-5Synonyms: N-Methyllycorine iodide
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Mukurozioside IIb
0 ImagesCat. No.: HY-N19872CAS No.: 103001-34-9Mukurozioside IIb is a sesquiterpene glycoside found in S. mukorossi and Sapindus rarak. Mukurozioside IIb can be used for the research of breast cancer.
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Ceftizoxime alapivoxil
0 ImagesCat. No.: HY-W780717CAS No.: 135821-54-4Synonyms: AS-924 free baseCeftizoxime alapivoxil AS-924 (free base) is an orally active prodrug of Ceftizoxime (HY-B1596). Ceftizoxime alapivoxil exhibits potent inhibitory effect against gram-positive and gram-negative bacteria. Ceftizoxime alapivoxil can be used for the research of bacterial infection.
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Stacofylline hydrochloride
0 ImagesCat. No.: HY-106412ACAS No.: 138472-18-1Synonyms: S 9977Stacofylline hydrochloride (S 9977), a Xanthine (HY-W017389) derivative, is a potent AChE inhibitor with an IC50 of 5-50 nM. Stacofylline shows anti-amnesic and promnesic activities.
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1,3-Dibromo-1,3-dichloroacetone
0 ImagesCat. No.: HY-133627CAS No.: 62874-84-41,3-Dibromo-1,3-dichloroacetone is a halogenated ozone-chlorine and ozone chloramine disinfection byproducts (DBPs) at elevated bromide levels when chlorine or chloramine is used as a secondary disinfectant.
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Quercetin-3-O-[α-L-rhamnose-(1→2)-β-D-glucopyranosyl]-5-O-β-D-glucopyranoside
![Quercetin-3-O-[α-L-rhamnose-(1→2)-β-D-glucopyranosyl]-5-O-β-D-glucopyranoside](https://file.medchemexpress.com/product_pic/hy-n18374.gif "Click to View Quercetin-3-O-[α-L-rhamnose-(1→2)-β-D-glucopyranosyl]-5-O-β-D-glucopyranoside Product Detail")
0 ImagesCat. No.: HY-N18374Quercetin-3-O--5-O-β-D-glucopyranoside is a flavone glycoside found in the seeds of Impatiens balsamina L.
