138472-18-1
138472-18-1
Chemical Structure
Stacofylline hydrochloride
Synonym(s): S 9977
- CAS No.: 138472-18-1
- Formula:C20H34ClN7O3
- Molecular Weight:455.98
IUPAC Name: N,N-diethyl-4-(3-(1,3,7-trimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)propyl)piperazine-1-carboxamide hydrochloride
InChIKey: GVHZRDKDUVIRNY-UHFFFAOYSA-N
SMILES: O=C1C2=C(N(C)C(N1C)=O)N=C(CCCN3CCN(CC3)C(N(CC)CC)=O)N2C.Cl
Biological Activity: Stacofylline hydrochloride (S 9977), a Xanthine (HY-W017389) derivative, is a potent AChE inhibitor with an IC50 of 5-50 nM. Stacofylline shows anti-amnesic and promnesic activities[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Stacofylline hydrochloride | Stacofylline hydrochloride (S 9977), a Xanthine (HY-W017389) derivative, is a potent AChE inhibitor with an IC50 of 5-50 nM. Stacofylline shows anti-amnesic and promnesic activities. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. L E Trudeau, et al. Xanthine derivatives IBMX and S-9977-2 potentiate transmission at an Aplysia central cholinergic synapse. Brain Res. 1992 Jul 17;586(1):78-85. [Content Brief]
- [2]. Roger D. Porsolt, et al. Potential cognition-enhancing properties of S 9977 in three moenls of amnesia in the mouse. Drug Development Research. 1992.
Keywords
