1. GPCR/G Protein
  2. GNRH Receptor
  3. Goserelin

Goserelin (Synonyms: ICI 118630)

Cat. No.: HY-13673
Handling Instructions

Goserelin(ICI 118630) is an injectable gonadotropin releasing hormone superagonist (GnRH agonist).

For research use only. We do not sell to patients.

Goserelin Chemical Structure

Goserelin Chemical Structure

CAS No. : 65807-02-5

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Description

Goserelin(ICI 118630) is an injectable gonadotropin releasing hormone superagonist (GnRH agonist). IC50 value: Target: GnRH agonist Goserelin is used to treat hormone-sensitive cancers of the breast (in pre- and peri- menopausal women) and prostate, and some benign gynaecological disorders (endometriosis, uterine fibroids and endometrial thinning). In addition, goserelin is used in assisted reproduction and in the treatment of precocious puberty. It may also be used in the treatment of male-to-female transsexuals and is favoured above other anti-androgens in some countries, such as the UK. It is available as a 1-month depot and a long-acting 3-month depot. Goserelin stimulates the production of the sex hormones testosterone and estrogen in a non-pulsatile (non-physiological) manner.

Clinical Trial
Molecular Weight

1269.41

Formula

C₅₉H₈₄N₁₈O₁₄

CAS No.

65807-02-5

SMILES

O=C([[email protected]@H](N1)CCC1=O)N[[email protected]@H](CC2=CNC=N2)C(N[[email protected]](C(N[[email protected]@H](CO)C(N[[email protected]](C(N[[email protected]](COC(C)(C)C)C(N[[email protected]@H](CC(C)C)C(N[[email protected]@H](CCCNC(N)=N)C(N3[[email protected]@H](CCC3)C(NNC(N)=O)=O)=O)=O)=O)=O)CC4=CC=C(O)C=C4)=O)=O)CC5=CNC6=C5C=CC=C6)=O

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Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

GoserelinICI 118630ICI118630ICI-118630GNRH ReceptorGonadotropin releasing hormone receptorGNRHRInhibitorinhibitorinhibit

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