Fungal
An antifungal agent is a drug that selectively eliminates fungal pathogens from a host with minimal toxicity to the host.
Classes: 1. Polyene Antifungal Drugs: Amphotericin, nystatin, and pimaricin interact with sterols in the cell membrane (ergosterol in fungi, cholesterol in humans) to form channels through which small molecules leak from the inside of the fungal cell to the outside. 2. Azole Antifungal Drugs: Fluconazole, itraconazole, and ketoconazole inhibit cytochrome P450-dependent enzymes (particularly C14-demethylase) involved in the biosynthesis of ergosterol, which is required for fungal cell membrane structure and function. 3. Allylamine and Morpholine Antifungal Drugs: lylamines (naftifine, terbinafine) inhibit ergosterol biosynthesis at the level of squalene epoxidase. The morpholine drug, amorolfine, inhibits the same pathway at a later step. 4. Antimetabolite Antifungal Drugs: 5-Fluorocytosine acts as an inhibitor of both DNA and RNA synthesis via the intracytoplasmic conversion of 5-fluorocytosine to 5-fluorouracil.
All Product Categories
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Fungal Related Products (2769)
Related Products (2769)
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Antibodies (1)
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Related Compound Screening Libraries (1)
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Iprovalicarb
0 ImagesCat. No.: HY-121766CAS No.: 140923-17-7Synonyms: Fencaramid; SZX-0722Iprovalicarb (Fencaramid; SZX-0722) is a fungicide that can be used for the study of fungal diseases in the wine sector.
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D13
0 ImagesCat. No.: HY-W514721CAS No.: 321945-27-1D13, an Acylhydrazones derivative, possesses antifungal activity. D13 is effective against murine sporotrichosis.
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Ametoctradin (Standard)
0 ImagesCat. No.: HY-W714076RCAS No.: 865318-97-4Ametoctradin (Standard) is the analytical standard of Ametoctradin. This product is intended for research and analytical applications. Ametoctradin is a potent Qo site inhibitor of bc1 complex in mitochondrial respiration. Ametoctradin is a highly selective and effective Oomycete-specific fungicide that can be used against late blight and downy mildews.
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Prothioconazole (Standard)
0 ImagesCat. No.: HY-116568RCAS No.: 178928-70-6Synonyms: JAU-6476 (Standard)Prothioconazole (Standard) is the analytical standard of Prothioconazole. This product is intended for research and analytical applications. Prothioconazole is a triazolinthione fungicide. Prothioconazole is a CYP51 inhibitor.
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Haliangicin B
0 ImagesCat. No.: HY-N14442CAS No.: 661466-85-9Haliangicin B has anti-filamentous fungi activity, and it also has effect on oomycetes, but has no antibacterial activity.
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Epelmycin E
0 ImagesCat. No.: HY-N14159CAS No.: 76264-93-2Epelmycin E has anti-Gram positive, negative bacteria and candida albicans activity, and has anti-leukemic L1210 activity, which is stronger than Aclacinomycin.
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Terrestribisamide
0 ImagesCat. No.: HY-N12267ACAS No.: 91000-13-4Synonyms: (E)-N,N′-DiferuloylputrescineTerrestribisamide ((E)-N,N′-Diferuloylputrescine) can be isolated from dried fruits of Tribulus terrestris. Terrestribisamide has antibacterial, antifungal, antioxidant, anticancer effects.
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Pneumocandin C0
0 ImagesCat. No.: HY-N14990CAS No.: 144074-96-4Pneumocandin C0 is the isomer of Pneumocandin B0 (HY-17578) with antifungal activity, which is found by carrying out fermentations of Glarea lozoyensis at a high residual fructose concentration.
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Methyl 3-(2-nitrophenyl)acrylate
0 ImagesCat. No.: HY-W1058381CAS No.: 612-43-1Methyl 3-(2-nitrophenyl) acrylate is an antifungal agent. Methyl 3-(2-nitrophenyl) acrylate exhibits activity against Candida albicans strains. Methyl 3-(2-nitrophenyl) acrylate can be used in research related to Candida albicans infections.
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BHBM
0 ImagesCat. No.: HY-156195CAS No.: 302807-84-7BHBM (compound 1) is an aromatic acylhydrazone antifungal agent with high bactericidal activity against Cryptococcus neoformans.
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YZK-C22
0 ImagesCat. No.: HY-163634CAS No.: 1111646-44-6YZK-C22, containing a 1,2,3-thiadiazol-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole skeleton, is a fungicide lead compound with broad-spectrum fungicidal activity.
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Neocopiamycin B
0 ImagesCat. No.: HY-N14817CAS No.: 113189-06-3Neocopiamycin B is found in the strain of Str. hygroscopicus var. crystallogenes. Neocopiamycin B has antifungal activity.
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Pyraoxystrobin
0 ImagesCat. No.: HY-W715372CAS No.: 862588-11-2Pyraoxystrobin is a QoI fungicide, with an EC50 of 0.0094 μg/mL for M. oryzae isolates. Pyraoxystrobin can be used for the research of M. oryzae in rice fields.
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Group II intron-IN-1
0 ImagesCat. No.: HY-170885CAS No.: 836644-25-8Group II intron-IN-1 (Compound 1) is an inhibitor of fungal Group II introns, with an IC50 of 3 μM. Group II intron-IN-1 can be used for research on infections caused by fungi such as Candida.
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Bis(4-morpholinyl)methane
0 ImagesCat. No.: HY-W175598CAS No.: 5625-90-1Synonyms: N,N'-Methylene-bis-morpholineBis(4-morpholinyl)methane (N,N'-Methylene-bis-morpholine) is a broad-spectrum, slow-release formaldehyde-based fungicide. Bis(4-morpholinyl)methane inhibits the growth and reproduction of microorganisms, and prevents spoilage and odor generation in humid environments. Bis(4-morpholinyl)methane serves as a preservative for natural rubber latex.
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Antifungal agent 89
0 ImagesCat. No.: HY-161049CAS No.: 3036399-40-0Antifungal agent 89 (compound 28) is a antifungal agent against Cryptococcus neoformans with minimum inhibitory concentration value ranging from 0.8 to 52.17 μM.
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Epoformin
0 ImagesCat. No.: HY-N14220CAS No.: 52146-62-0Epoformin, is a fungal cyclohexene epoxide that can be isolated from Diplodia quercivora. Epoformin is an antibiotic and exhibits weak inhibitory activity against rye seedling sheath growth. Epoformin exhibits antifungal activity, inhibits Phytophthora cinnamomi and Phytophthora plurivora.
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SDH-IN-40
0 ImagesCat. No.: HY-179139SDH-IN-40 (compound A7) is a succinate dehydrogenase inhibitor (SDHI). SDH-IN-40 exhibits strong inhibitory effects on F. graminearum (IC50 = 34.33 μM). SDH-IN-40 can be used for research on fungal infections.
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Epelmycin A
0 ImagesCat. No.: HY-N14155CAS No.: 107807-25-0Epelmycin A has anti-Gram positive, negative bacteria and candida albicans activity, and has anti-leukemic L1210 activity, which is stronger than Aclacinomycin.
