2. Signaling Pathways
  3. Anti-infection
  4. Fungal

Fungal

Fungal

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An antifungal agent is a drug that selectively eliminates fungal pathogens from a host with minimal toxicity to the host.

Classes: 1. Polyene Antifungal Drugs: Amphotericin, nystatin, and pimaricin interact with sterols in the cell membrane (ergosterol in fungi, cholesterol in humans) to form channels through which small molecules leak from the inside of the fungal cell to the outside. 2. Azole Antifungal Drugs: Fluconazole, itraconazole, and ketoconazole inhibit cytochrome P450-dependent enzymes (particularly C14-demethylase) involved in the biosynthesis of ergosterol, which is required for fungal cell membrane structure and function. 3. Allylamine and Morpholine Antifungal Drugs: lylamines (naftifine, terbinafine) inhibit ergosterol biosynthesis at the level of squalene epoxidase. The morpholine drug, amorolfine, inhibits the same pathway at a later step. 4. Antimetabolite Antifungal Drugs: 5-Fluorocytosine acts as an inhibitor of both DNA and RNA synthesis via the intracytoplasmic conversion of 5-fluorocytosine to 5-fluorouracil.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N14247
    Exfoliazone
    		Inhibitor
    Exfoliazone is a phenoxazine antibiotic. Exfoliazone has the activity of resisting Valsa ceratosperma, and the ED50 that inhibits mycelial growth is 70 μg/mL.
    Exfoliazone
  • HY-B0914B
    10-Undecenoic acid (copper)
    		Inhibitor
    10-Undecenoic acid copper (Undecylenic acid copper) is an antifungal agent. 10-Undecenoic acid copper inhibits Aβ oligomerization, scavenges ROS and inhibits μ-calpain activity. 10-Undecenoic acid copper has neuroprotective effects. 10-Undecenoic acid copper has anticancer effects on a variety of tumors. 10-Undecenoic acid copper inhibits C. albicans biofilm formation and MRSA infection. 10-Undecenoic acid copper inhibits quorum sensing signals of Bacillus subtilis and Pseudomonas aeruginosa.
    10-Undecenoic acid (copper)
  • HY-N14532
    Pyrrolomycin E
    		Inhibitor
    Pyrrolomycin E is a pyrrole antibiotic. Pyrrolomycin E has anti-Gram-positive bacteria, anti-Gram-negative bacteria and anti-individual fungi activity.
    Pyrrolomycin E
  • HY-N13221
    Apple Cider Vinegar Powder
    		Inhibitor
    Apple Cider Vinegar Powder is a soluble powdered form of apple cider vinegar. Apple Cider Vinegar Powder has anti-bacterial, anti-oxidant, and antibiotic properties and can help maintain the acid-base balance in the blood. Apple Cider Vinegar Powder can lower blood sugar and lipid levels. Apple Cider Vinegar Powder is used in research related to tumors, diabetes, and cardiovascular diseases.
    Apple Cider Vinegar Powder
  • HY-N14022
    Glidobactin F
    		Inhibitor
    Glidobactin F is an anti-tumor antibiotic. Glidobactin F has the activity against pathogenic fungi and yeast. Glidobactin F also extends the survival of mice inoculated with leukemia P388 cells.
    Glidobactin F
  • HY-N13993
    Aranorosinol A
    		Inhibitor
    Aranorosinol A is a secondary metabolite with weak antibacterial and antifungal properties.
    Aranorosinol A
  • HY-W021040R
    Fludioxonil (Standard)
    		Inhibitor
    Fludioxonil (Standard) is the analytical standard of Fludioxonil. This product is intended for research and analytical applications. Fludioxonil, a phenylpyrrole fungicide, has a strong inhibition on mycelia growth of S. sclerotiorum.
    Fludioxonil (Standard)
  • HY-105752
    Loflucarban
    		Inhibitor
    Loflucarban (Fluonilid) is a potent antimycotic agent. Loflucarban can be used for the research of the ear infections.
    Loflucarban
  • HY-17535
    Methasulfocarb
    		Inhibitor
    Methasulfocarb is a fungicide compound.
    Methasulfocarb
  • HY-101506
    2,4,6-Tribromophenyl caproate
    		Inhibitor 98.29%
    2,4,6-Tribromophenyl caproate (2,4,6-tribromophenyl caproic acid ester) is an anti-fungal agent.
    2,4,6-Tribromophenyl caproate
  • HY-U00311
    Aliconazole
    		Inhibitor
    Aliconazole is an antifungal imidazole derivative.
    Aliconazole
Cat. No. Product Name / Synonyms Application Reactivity