Guanylate Cyclase Ligand
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DOTA-MLN6907
0 ImagesCat. No.: HY-P12379CAS No.: 1792977-97-9DOTA-MLN6907 is a guanylate cyclase C (GCC) binding agent. DOTA-MLN6907 competitively binds GCC receptors in vitro with an IC50 of approximately 4.6 nM. DOTA-MLN6907, after labeling with Ga-68, can specifically bind to GCC-expressing cancer cells for PET imaging. DOTA-MLN6907 can be used for PET imaging studies of GCC-expressing tumors such as colorectal cancer and for stratified assessment of GCC expression levels.
