IKK-α Activator
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SMU-H1
0 ImagesCat. No.: HY-189658CAS No.: 2410782-67-9SMU-H1 is a TLR2 agonist with a KD of 12.1 nM for mouse TLR2 and an EC50 of 5.14 nM in HEK-Blue hTLR2 cells. SMU-H1 binds TLR2 and activates MyD88-dependent signaling. SMU-H1 activates the NF-κB and MAPK signaling pathways. SMU-H1 induces proinflammatory cytokine production. SMU-H1 promotes M1 macrophage polarization and dendritic cell activation. SMU-H1 can be used for research on Lewis lung cancer.
