Neurokinin Receptor Inhibitor
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Aprepitant
0 ImagesSynonyms: MK-0869; MK-869; L-754030Aprepitant (MK-0869) is a selective and high-affinity neurokinin 1 receptor antagonist with a Kd of 86 pM.
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Aprepitant (Standard)
0 ImagesSynonyms: MK-0869 (Standard); MK-869 (Standard); L-754030 (Standard)Aprepitant (Standard) is the analytical standard of Aprepitant. This product is intended for research and analytical applications. Aprepitant (MK-0869) is a selective and high-affinity neurokinin 1 receptor antagonist with a Kd of 86 pM.
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Fosnetupitant
0 ImagesCat. No.: HY-17615CAS No.: 1703748-89-3Synonyms: PronetupitantFosnetupitant (Pronetupitant) a methylene phosphate proagent of Netupitant. Fosnetupitant (Pronetupitant) exhibits a pKi of 9.5 for human NK1 receptor.
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Benzomalvin B
0 ImagesCat. No.: HY-114673CAS No.: 157047-97-7Benzomalvin B is the less active analogs of Benzomalvin A. Benzomalvin B is weakly active against substance P.
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NK3R-IN-1
0 ImagesCat. No.: HY-149358CAS No.: 2854331-14-7NK3R-IN-1 (compound 16x), a imidazolepiperazine derivative, is an orally active Neurokinin Receptor NK3R inhibitor. NK3R-IN-1 decreases blood luteinizing hormone levels in ovariectomy (OVX) model.
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MEDI-1912
0 ImagesCat. No.: HY-P991323MEDI-1912 is a human monoclonal antibody (mAb) targeting NGF/bNGF. MEDI-1912 inhibits signaling through TrkA and p75 receptors. MEDI-1912 can be used in chronic pain research.
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SR140333B
0 ImagesCat. No.: HY-161835CAS No.: 155418-06-7SR140333B is a selective NK1 receptor inhibitor that can reduce LPS-induced fever and mitigate LPS (HY-D1056)-induced changes in brain tissue in rats.
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SCH 60057
0 ImagesCat. No.: HY-157743CAS No.: 203061-35-2SCH 60057 (Compound 7) is a neurokinin (NK) receptor inhibitor that can be isolated from Acremonium sp., with IC50 values of 6 μM and 12 μM for NK1 and NK2, respectively.
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Aprepitant-13C2,d2 (Major)
0 ImagesCat. No.: HY-W777166CAS No.: 1217676-37-3Synonyms: MK-0869--13C2,d2; MK-869-13C2,d2; L-754030--13C2,d2Aprepitant-13C2,d2 (Major) (MK-0869-13C2,d2) is 13C labeled Aprepitant. Aprepitant (MK-0869) is a selective and high-affinity neurokinin 1 receptor antagonist with a Kd of 86 pM.
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Dazodeunetant
0 ImagesCat. No.: HY-177079SCAS No.: 2759134-55-7Dazodeunetant (Example 56) is a nitrogen-containing fused ring derivative. Dazodeunetant is an inhibitor of neurokinin (NK). Dazodeunetant has an IC50 0f 75.99 nM against NK3R in HEK293-NK3 (IP1). Dazodeunetant can be studied in research for menopausal hot flashes.
