Nucleoside Antimetabolite/Analog
Nucleoside analogues are molecules that act like nucleosides in DNA synthesis. They include a range of antiviral products used to prevent viral replication in infected cells. Nucleoside analogues can be used against hepatitis B virus, hepatitis C virus, herpes simplex, and HIV. Once they are phosphorylated, they work as antimetabolites by being similar enough to nucleotidesto be incorporated into growing DNA strands. Less selective nucleoside analogues are used as chemotherapy agents to treat cancer, eg gemcitabine and 5-FU. Antimetabolite is a chemical that inhibits the use of a metabolite, which is another chemical that is part of normal metabolism. Such substances are often similar in structure to the metabolite that they interfere with, such as the antifolates that interfere with the use of folic acid. The presence of antimetabolites can have toxic effects on cells, such as halting cell growth and cell division, so these compounds are used as chemotherapy for cancer.
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Nucleoside Antimetabolite/Analog 관련 제품 (2437)
관련 제품 (2437)
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5-β-D-Ribofuranosyl-2(1H)-pyridinone
0 ImagesCat. No.: HY-152747CAS No.: 188871-50-35-β-D-Ribofuranosyl-2(1H)-pyridinone is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
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7-Methylguanosine 5'-Monophosphate-d3
0 ImagesCat. No.: HY-W754649CAS No.: 22976-65-47-Methylguanosine 5'-Monophosphate-d3 is the deuterium labeled 7-Methylguanosine 5′-monophosphate (HY-173169). 7-Methylguanosine 5′-monophosphate (7-Methylguanylic acid) is a building block of nucleic acid.
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Homouridine
0 ImagesCat. No.: HY-154698CAS No.: 30685-57-5
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N6-Benzoyl-3’-O-(2-methoxyethyl)adenosine
0 ImagesCat. No.: HY-152503CAS No.: 256223-99-1N6-Benzoyl-3’-O-(2-methoxyethyl)adenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
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5-Nitro-1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-2(1H)-pyridinone
0 ImagesCat. No.: HY-W556327CAS No.: 59892-37-45-Nitro-1-(2,3,5-tri-O-benzoyl-β-D-ribofuranosyl)-2(1H)-pyridinone is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
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2’,3’-Di-O-acetyl-8-benzyloxy-3’-deoxy guanosine
0 ImagesCat. No.: HY-154360CAS No.: 2389988-71-82’,3’-Di-O-acetyl-8-benzyloxy-3’-deoxy guanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
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3’-O-MOE-U-2’-phosphoramidite
0 ImagesCat. No.: HY-154544CAS No.: 1452849-90-93’-O-MOE-U-2’-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
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15H-11,12-EETA
0 ImagesCat. No.: HY-180664CAS No.: 877878-78-915H-11,12-EETA is a nucleoside metabolite.
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2’-Chloro-N6-(4-methoxy)benzyl adenosine
0 ImagesCat. No.: HY-152332CAS No.: 722504-77-02’-Chloro-N6-(4-methoxy)benzyl adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
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2-Amino-8-aza-7-deaza-7-iodoguanosine
0 ImagesCat. No.: HY-152831CAS No.: 1997362-13-62-Amino-8-aza-7-deaza-7-iodoguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
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3-(Methylseleninyl)-L-alanine
0 ImagesCat. No.: HY-180708CAS No.: 326794-77-83-(Methylseleninyl)-L-alanine is a nucleoside metabolite.
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3-Deoxy-1,2:5,6-bis-O-(1-methylethylidene)-α-D-ribo-hexofuranose
0 Images3-Deoxy-1,2:5,6-bis-O-(1-methylethylidene)-α-D-ribo-hexofuranose is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
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2'-Deoxy-8-methylamino-adenosine
0 ImagesCat. No.: HY-154012CAS No.: 13389-10-12'-Deoxy-8-methylamino-adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
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2-Amino-N6,N6-dimethyl-2’-deoxy-2’-fluoro-beta-D-arabino-adenosine
0 ImagesCat. No.: HY-152485CAS No.: 2171103-80-12-Amino-N6,N6-dimethyl-2’-deoxy-2’-fluoro-beta-D-arabino-adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
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N6-Threonylcarbamoyladenosine-13C4,15N
0 ImagesCat. No.: HY-W780282CAS No.: 1195030-28-4Synonyms: N6-(N-Threonylcarbonyl)adenosine-13C4,15NN6-Threonylcarbamoyladenosine-13C4,15N (N6-(N-Threonylcarbonyl)adenosine-13C4,15N) is the 13C- and 15N-labeled N6-Threonylcarbamoyladenosine (HY-18398). N6 - Threonylcarbamoyladenosine is a common nucleosides, which can decorate and become tRNA.
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3’-Deoxy-3’,5-difluorocytidine
0 ImagesCat. No.: HY-152308CAS No.: 661470-65-13’-Deoxy-3’,5-difluorocytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
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2’-O-(2-Methoxyethyl)guanosine 5’-triphosphate ammonium
0 ImagesCat. No.: HY-1541212’-O-(2-Methoxyethyl)guanosine 5’-triphosphate (ammonium) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
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5-[[Methyl(2,2,2-trifluoroacetyl)amino]methyl]-2-thiouridine
![5-[[Methyl(2,2,2-trifluoroacetyl)amino]methyl]-2-thiouridine](https://file.medchemexpress.com/product_pic/hy-152735.gif "Click to View 5-[[Methyl(2,2,2-trifluoroacetyl)amino]methyl]-2-thiouridine Product Detail")
0 ImagesCat. No.: HY-152735CAS No.: 89128-99-45-[[Methyl(2,2,2-trifluoroacetyl)amino]methyl]-2-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
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2’-Deoxy-3’,2-anhydrouridine
0 ImagesCat. No.: HY-154248CAS No.: 26922-44-12’-Deoxy-3’,2-anhydrouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
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TLR7 agonist 11
0 ImagesCat. No.: HY-149072CAS No.: 2389988-36-5TLR7 agonist 11 is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
