2. Signaling Pathways
  3. Cell Cycle/DNA Damage
    Epigenetics
  4. Sirtuin
  5. SIRT1 Isoform
  6. SIRT1 Agonist

SIRT1 Agonist

SIRT1 Agonist (1):

Cat. No. Product Name Effect Purity
  • HY-138443A
    BF-175
    		Agonist
    BF-175 is a selective SIRT1 agonist. BF175 increases SIRT1-mediated activation of PGC1-α, induces Apoptosis, induces Autophagy and inhibits SREBP activity. BF-175 protects against high glucose-mediated mitochondrial injury. BF-175 attenuates diabetic kidney disease progression. BF175 inhibits endometrial carcinoma.