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  4. Fluorescent Dye

Fluorescent Dye

Fluorescence is a phenomenon of photoluminescence in luminescence. When an atom is irradiated by light, some electrons around the nucleus jump from their original orbitals to higher energy orbitals under the influence of light energy, i.e., from the ground state to the first or second excited single-line state, etc. Due to the instability of the first or second excited singlet state, the electron returns from the excited singlet state to the ground state accompanied by released energy, resulting in fluorescence.

Fluorescent dyes can be covalently bound or physically adsorbed in the structure of the substance. The fluorescence properties allow for the characterization, localization and quantitative analysis of the labeled object. Fluorescent dyes have shown great potential for the detection of proteins, nucleic acids, cells, and immunoassays, attributed to the advantages in non-radioactive contamination, simple experimental operation and easy observation.

Fluorescent dyes have penetrated many fields such as pharmacology, physiology, environmental science, and information science, as well as functional studies of proteins and drug screening.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-111956A
    D-Ala-Lys-AMCA TFA
    D-Ala-Lys-AMCA TFA is a known proton-coupled oligopeptide transporter 1 (PEPT1) substrate that emits blue fluorescence. D-Ala-Lys-AMCA TFA may be transported into liver cancer cells and Caco-2 cells based on fluorescence analysis. D-Ala-Lys-AMCA TFA can be used for characterizing PEPT1-specific substrates or inhibitors (Ex/Em = 390/480 nm).
    D-Ala-Lys-AMCA TFA
  • HY-D1767
    Tempocholine
    Tempocholine is a polar tracer.
    Tempocholine
  • HY-160040D
    Cy3 labled Cobitolimod sodium
    Cy3 labled Cobitolimod sodium is a Cy3 labled Cobitolimod sodium.
    Cy3 labled Cobitolimod sodium
  • HY-D1957
    ATTO 633 NHS ester
    ATTO 633 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 633 NHS ester is an NHS ester derivative of ATTO 633 that can be used to label proteins or antibodies.
    ATTO 633 NHS ester
  • HY-P11406
    Ac-RSLK-AMC
    Ac-RSLK-AMC is a fluorogenic substrate, can be used to measure the enzymatic activities of site-1 protease (S1P).
    Ac-RSLK-AMC
  • HY-177636C
    FAM labled GPI2A sodium
    FAM labled GPI2A sodiumis a FAM labled GPI2A sodium.
    FAM labled GPI2A sodium
  • HY-D0450
    C.I. Pigment red 112
    C.I. Pigment red 112 is the most important colorant used to add color or change the color of something and is chemically essentially unaffected by the carrier or medium into which it is incorporated. It can be widely used in textile, medicine, food, cosmetics, plastics, paint, ink, photography and paper industries.
    C.I. Pigment red 112
  • HY-D2840
    FITC-mPEG350
    FITC-mPEG350 is a fluorescent dye composed of methoxypolyethylene glycol (mPEG) and FITC (HY-66019). FITC-mPEG350 can be used for fluorescent labeling and imaging.
    FITC-mPEG350
  • HY-132606D
    FAM labled Nedosiran sodium
    FAM labled Nedosiran sodiumis a FAM labled Nedosiran sodium.
    FAM labled Nedosiran sodium
  • HY-D0095
    B261
    B261 is a multifunctional dye. Dyes are important tools in biological experiments. They can help researchers observe and analyze cell structures, track biomolecules, evaluate cell functions, distinguish cell types, detect biomolecules, study tissue pathology and monitor microorganisms. Their applications range from basic scientific research to clinical A wide range of diagnostics. Dyes are also widely used in traditional fields such as textile dyeing, as well as in emerging fields such as functional textile processing, food pigments and dye-sensitized solar cells.
    B261
  • HY-D2019
    ATTO 550 NHS ester
    ATTO 550 NHS ester is a new fluorescent marker based on the Rhodamine structure. It has strong absorption, high fluorescence quantum yield, high thermal stability and photochemical stability, and is suitable for single molecule detection and high-resolution microscopy. ATTO 550 NHS ester is an NHS ester derivative of ATTO 550 that can be used to label proteins or antibodies.
    ATTO 550 NHS ester
  • HY-D3222
    NIR-PN1
    NIR-PN1 is a blood-brain barrier-permeable near-infrared fluorescent indicator targeting peroxynitrite anion (ONOO−) (Ex/Em = 510 nm/670 nm). NIR-PN1 reacts with ONOO− to trigger a strong near-infrared fluorescence enhancement, enabling the detection of ONOO− flux. NIR-PN1 allows the imaging of ONOO− flux in various Parkinson's disease models. NIR-PN1 is applicable to Parkinson's disease-related research.
    NIR-PN1
  • HY-165424
    NIR-BG2
    NIR-BG2 is a near-infrared fluorescent probe targeting senescence-associated β-galactosidase (SA-β-Gal). NIR-BG2 is activated by SA-β-Gal and undergoes hydrolysis to release electrophilic quinone methide that covalently binds to surrounding proteins for in situ labeling, with a 16-fold enhancement of fluorescence signal at 709 nm . NIR-BG2 is promising for research of vivo imaging of cellular senescence.
    NIR-BG2
  • HY-P4465
    Gly-Arg-pNA
    Gly-Arg-pNA is a fluorogenic substrate for the measurement of protease activity. Gly-Arg-pNA undergoes hydrolysis and releases the fluorescent product p-nitroaniline. p-nitroaniline is in a fluorescent state under ultraviolet light irradiation and can emit a fluorescent signal .
    Gly-Arg-pNA
  • HY-D1867
    Sulfo-Cy3-PEG2-TCO disodium
    Sulfo-Cy3-PEG2-TCO disodium is a derivative of Cy3 (Cyanine3) (HY-D0822) dye containing sulfonate and TCO groups. The TCO groups of Sulfo-Cy3-PEG2-TCO disodium react with tetrazine functional groups in highly specific click chemistry to form covalent bonds. Thus, Sulfo-Cy3-PEG2-TCO disodium can be covalently bound to some biomolecules (especially antibodies, proteins, etc.) to track their location and dynamic changes in biological samples.
    Sulfo-Cy3-PEG2-TCO disodium
  • HY-D2228
    IR-7
    IR-7 is a mitochondria-targeted heptamethylindocyanine dye, and can used for cancer study.
    IR-7
  • HY-135414A
    Cyanine5 NHS ester bromide
    Cyanine5 NHS ester bromide is a active compound, can be used to label amino groups in peptides, proteins, and oligonucleotides. Cyanine5 NHS ester bromide is a cyanine dye, fluorescence-labeling neurotensin (8-13) via arginine residues.
    Cyanine5 NHS ester bromide
  • HY-159697D
    Cy3 labled ISIS 532401 sodium
    Cy3 labled ISIS 532401 sodium is a Cy3 labled ISIS 532401 sodium.
    Cy3 labled ISIS 532401 sodium
  • HY-D1201
    Pigment Red 245
    Pigment Red 245 is a commonly used commercial dye for bulk coloring of plastics and synthetic fibers and for surface coatings such as paints and inks.
    Pigment Red 245
  • HY-D3311
    M1219
    M1219 is a GSH/ATP dual near-infrared activated fluorescent probe that enables independent real-time monitoring of dynamic changes in intracellular GSH and ATP without spectral crosstalk (GSH: Ex=640 nm, Em=740~800 nm; ATP: Ex=594 nm/610 nm, Em=650~700 nm). M1219 not only visualizes the metabolic regulatory mechanism of TNBC under single/dual-target inhibition of SLC7A11/GLUT1 and accurately evaluates its in vivo efficacy, but also achieves precise localization of the TNBC tumor invasion boundary. M1219 can be used for the research of triple-negative breast cancer.
    M1219
Cat. No. Product Name / Synonyms Application Reactivity