Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitors (4)

Isotope-Labeled Compounds Related Products (10876):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-B0710S

Betaine-¹³C₃		99.86%
Betaine-¹³C₃ (Trimethylglycine-¹³C₃) is the ¹³C labeled isotope of Betaine (HY-B0710). Betaine (Trimethylglycine) is a natural compound found in many foods and also an active methyl-donor which can maintain normal DNA methylation patterns^[1,2]. Betaine is found ubiquitously in plants, animals, microorganisms, and rich dietary sources including seafood, spinach, and wheat bran. Betaine also acts as an osmolyte, to maintain the avian’s cellular water and ion balance to improve the avian’s capacity against heat stress via preventing dehydration and osmotic inactivation. It helps in maintaining the protective osmolytic activity, especially in heat-stressed birds. Betaine may promote various intestinal microbes against osmotic variations and thus improve microbial fermentation activity.

HY-W004260S2

Arachidic acid-d₃
Arachidic acid-d₃ is the deuterium labeled Arachidic acid (HY-W004260). Arachidic acid (Eicosanoic acid) is a long-chain saturated fatty acid. Arachidic acid can be found in the human organism from the plasma phospholipid, fish, cannabis and other plant oils. Arachidic acid conjugated with Chitosan oligosaccharide (HY-112108) can be used for anti-cancer drug delivery research.

HY-W017086S

Dibenzo[b,d]furan-d₈		99.90%
Dibenzo[b,d]furan-d₈ is the deuterium labeled Dibenzo[b,d]furan.

HY-116258S

C16 Ceramide-d₇ (d16:1,C16:0)		99.9%
C16 Ceramide-d₇ (d16:1,C16:0) is the deuterium labeled C16 Ceramide (d16:1,C16:0).

HY-34449S

Methylboronic acid-d₃		99.82%
Methylboronic acid-d₃ is the deuterium labeled Methylboronic acid (HY-34449). Methylboronic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

HY-W001171S

3-Hydroxyanthranilic acid-d₃		99.28%
3-Hydroxyanthranilic acid-d₃ is deuterium-labeled 3-Hydroxyanthranilic acid (HY-W001171).

HY-142567S

Pregnanetriol-d₄		99.84%
Pregnanetriol-d₄ is the deuterium labeled Pregnanetriol.

HY-W013636S2

2-Ketoglutaric acid-d₆		98.62%
2-Ketoglutaric acid-d₆ (Alpha-Ketoglutaric acid-d₆) is the deuterium labeled 2-Ketoglutaric acid (HY-W013636). 2-Ketoglutaric acid is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid is a reversible inhibitor of tyrosinase (IC₅₀=15 mM).

HY-W150598S

N-Nitrosopiperidine-d₁₀		98.20%
N-Nitrosopiperidine-d₁₀ is the deuterium labeled N-Nitrosopiperidine.

HY-B0356AS1

Ciprofloxacin-¹³C₃,¹⁵N monohydrochloride		99.9%
Ciprofloxacin-¹³C₃,¹⁵N (Bay-09867-¹³C₃,¹⁵N) monohydrochloride is ¹³C- and ¹⁵N-labeled Ciprofloxacin (monohydrochloride) (HY-B0356A).

HY-134575S

C24:1-Ceramide-d₇		99.9%
C24:1-Ceramide-d₇ is the deuterium labeled C24:1-Ceramide.

HY-N2026S1

Propylparaben-d₄		99.55%
Propylparaben-d₄ (Propyl parahydroxybenzoate-d4) is the deuterium labeled Propylparaben (HY-N2026). Propylparaben (Propyl parahydroxybenzoate) is an antibacterial preservative that can be produced by plants and bacteria. Propylparaben is an orally active weak estrogen receptor agonist. Propylparaben regulates the PI3K-AKT and JNK signaling pathways, and induces oxidative stress. Propylparaben is commonly used in cosmetics, pharmaceuticals and foods, and can be used in studies related to ovarian aging and myocardial ischemia-reperfusion injury.

HY-128995AS

Glycyl-Exatecan-d₅ hydrochloride		98.97%
Glycyl-Exatecan-d₅ (Glycyl-DX-8951-d₅) hydrochloride is deuterium labeled Glycyl-Exatecan (HY-128995A). Glycyl-Exatecan (Glycyl-DX-8951), a derivative of Exatecan (HY-13631), is an anticancer agent. Glycyl-Exatecan has significantly antitumor activity. Glycyl-Exatecan can be used for cancers like solid tumors research.

HY-Y0248AS

(E,E)-Farnesol-d₆		98.71%
(E,E)-Farnesol-d₆ (trans,trans-Farnesol-d₆) is deuterium labeled (E,E)-Farnesol (HY-Y0248). (E,E)-Farnesol (trans,trans-Farnesol) is a quorum-sensing molecule of Candida species. (E,E)-Farnesol can inhibit the growth, metabolism and biofilm formation of various Candida species, and affect their morphology and invasiveness.

HY-113603S

Tildacerfont-d₈		99.97%
Tildacerfont-d₈ (SPR001-d₈; LY2371712-d₈) is a deuterium labeled Tildacerfont (HY-113603). Tildacerfont (SPR001; LY2371712) is an orally active, blood-brain barrier-penetrant selective corticotropin-releasing factor type 1 (CRF1) receptor antagonist. Tildacerfont selectively blocks CRF1 receptors, thereby inhibiting the release of pituitary adrenocorticotropic hormone (ACTH). Tildacerfont can be used in research related to congenital adrenal hyperplasia.

HY-W012926S1

Dihydrouracil-d₄		99.97%
Dihydrouracil-d₄ is the deuterium labeled Dihydrouracil. Dihydrouracil (HY-W012926), a metabolite of Uracil, can be used as a marker for identification of dihydropyrimidine dehydrogenase (DPD)-deficient.

HY-Y0921S

(±)-1,2-Propanediol-d₈		99.55%
(±)-1,2-Propanediol-d₈ is the deuterium labeled (±)-1,2-Propanediol. (±)-1,2-Propanediol (1,2-(RS)-Propanediol) is an aliphatic alcohol and frequently used as an excipient in many agent formulations to increase the solubility and stability of agents.

HY-N0733S3

Glucosamine-6-¹³C hydrochloride		98.0%
Glucosamine-6-¹³C (hydrochloride) is the ¹³C labeled Glucosamine hydrochloride. Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as

HY-165607S

MCB-22-174		99.78%
MCB-22-174 is a deuterated Piezo1 agonist, with an EC₅₀ value of 6.28 μM. MCB-22-174 remarkably activates the CaMKII/ERK signaling pathway and initiates Ca²⁺ influx in rMSCs. MCB-22-174 significantly decreases the expression of chondrogenesis markers (Comp, Acan) and adipogenesis markers (Lpl, Fabp4) in MSCs. MCB-22-174 can effectively improve bone quality in hind-limb unloading (HU) model rats. MCB-22-174 can be used for the study of disuse osteoporosis (OP).

HY-Y0966S10

Glycine-d₃		99.97%
Glycine-d₃ is the deuterium labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors.

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