2. Cell Cycle/DNA Damage Metabolic Enzyme/Protease
  3. DNA/RNA Synthesis Endogenous Metabolite
  4. 5-Methylcytosine

5-Methylcytosine 

Cat. No.: HY-W008091 Purity: 99.66%
COA Handling Instructions

5-Methylcytosine is a well-characterized DNA modification, and is also predominantly in abundant non-coding RNAs in both prokaryotes and eukaryotes. 5-Methylcytosine in mRNA is a new epitranscriptome marker inArabidopsis, and that regulation of this modification is an integral part of gene regulatory networks underlying plant development.

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5-Methylcytosine Chemical Structure

5-Methylcytosine Chemical Structure

CAS No. : 554-01-8

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Solid + Solvent
10 mM * 1 mL in DMSO
ready for reconstitution
 USD 28 In-stock
Solution
10 mM * 1 mL in DMSO USD 28 In-stock
Solid
500 mg USD 25 In-stock
1 g USD 40 In-stock
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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of 5-Methylcytosine:

5-Methylcytosine Related Antibodies

Top Publications Citing Use of Products

1 Publications Citing Use of MCE 5-Methylcytosine

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

5-Methylcytosine is a well-characterized DNA modification, and is also predominantly in abundant non-coding RNAs in both prokaryotes and eukaryotes. 5-Methylcytosine in mRNA is a new epitranscriptome marker inArabidopsis, and that regulation of this modification is an integral part of gene regulatory networks underlying plant development[1].

IC50 & Target

Microbial Metabolite

 

Human Endogenous Metabolite

 

Molecular Weight

125.13

Appearance

Solid

Formula

C5H7N3O
CAS No.
SMILES

O=C1N=CC(C)=C(N)N1
Structure Classification
Initial Source

prokaryotes and eukaryotes
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 7.14 mg/mL (57.06 mM; Need ultrasonic)

DMSO : 5 mg/mL (39.96 mM; ultrasonic and warming and heat to 80°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 7.9917 mL 39.9584 mL 79.9169 mL
5 mM 1.5983 mL 7.9917 mL 15.9834 mL
10 mM 0.7992 mL 3.9958 mL 7.9917 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  PBS

    Solubility: 6.67 mg/mL (53.30 mM); Clear solution; Need ultrasonic

  • 2.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% Saline

    Solubility: ≥ 0.83 mg/mL (6.63 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in Saline)

    Solubility: ≥ 0.83 mg/mL (6.63 mM); Clear solution

  • 4.

    Add each solvent one by one:  10% DMSO    90% Corn Oil

    Solubility: ≥ 0.83 mg/mL (6.63 mM); Clear solution

*All of the co-solvents are available by MedChemExpress (MCE).
Purity & Documentation

Purity: 99.82%

COA (247 KB) HNMR (91 KB) LCMS (130 KB)

Handling Instructions (2659 KB)
References
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5-Methylcytosine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

5-Methylcytosine554-01-8DNA/RNA SynthesisEndogenous MetaboliteInhibitorinhibitorinhibit

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