2. Signaling Pathways
  3. Others
  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (10873):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W741652
    2-(2-Chloroethyl-d4)-1H-isoindole-1,3-dione
    2-(2-Chloroethyl-d4)-1H-isoindole-1,3-dione is the deuterium labeled 2-(2-Chloroethyl)isoindoline-1,3-dione (HY-W014424).
    2-(2-Chloroethyl-d<sub>4</sub>)-1H-isoindole-1,3-dione
  • HY-W701263
    2-[(Diphenylmethyl)thio]acetic Acid-d10
    2-[(Diphenylmethyl)thio]acetic Acid-d10 is the deuterium labeled 2-(Benzhydrylthio)acetic acid (HY-Y0092).
    2-[(Diphenylmethyl)thio]acetic Acid-d<sub>10</sub>
  • HY-W700739
    5-(2-Bromoethyl-1,1,2,2-d4)-2,3-dihydrobenzofuran
    5-(2-Bromoethyl-1,1,2,2-d4)-2,3-dihydrobenzofuran is the deuterium labeled 5-(2-Bromoethyl)-2,3-dihydrobenzofuran (HY-75250).
    5-(2-Bromoethyl-1,1,2,2-d<sub>4</sub>)-2,3-dihydrobenzofuran
  • HY-B1218S
    Sulfaphenazole-d4
    		99.66%
    Sulfaphenazole-d4 is the deuterium labeled Sulfaphenazole (HY-B1218). Sulfaphenazole is a selective inhibitor of human cytochrome P450 (CYP) 2C9 enzyme. Sulfaphenazole is a cytoprotective agent against light-induced death of photoreceptors. Sulfaphenazole inhibits light-induced necrosis and mitochondrial stress-initiated apoptosis. Sulfaphenazole is an off patent sulfonamide antibiotic and demonstrates bactericidal activity through enhanced M1 macrophage activity. Sulfaphenazole can significantly reduce infarct size and restore post-ischemic coronary flow following ischemia and reperfusion.
    Sulfaphenazole-d<sub>4</sub>
  • HY-155227S
    ALK/EGFR-IN-1-d5
    ALK/EGFR-IN-1-d5 (Compound (-)-9a) is a deuterated dual-target inhibitor of EGFR and ALK, with an IC50 of 1.08 nM for EGFR and an IC50 of 2.395 nM for ALK. ALK/EGFR-IN-1-d5 inhibits the phosphorylated proteins in the EGFR, ALK, and BRK signaling pathways, blocking the cell cycle, leading to a reduction in mitochondrial membrane potential and cell apoptosis (Apoptosis). ALK/EGFR-IN-1-d5 also significantly inhibits tumor growth in animal models and demonstrates good safety. ALK/EGFR-IN-1-d5 holds promise for research in the field of cancer treatment
    ALK/EGFR-IN-1-d<sub>5</sub>
  • HY-178369S
    Cyhalothrin-d9
    Cyhalothrin-d9 is the deuterium labeled Cyhalothrin (HY-111991). Cyhalothrin is a pyrethroid, a class of man-made insecticides that mimic the structure and insecticidal properties of the naturally-occurring insecticide pyrethrum which comes from the flowers of chrysanthemums.
    Cyhalothrin-d<sub>9</sub>
  • HY-101474BS
    (R)-Zanubrutinib-d5
    (R)-Zanubrutinib-d5 is deuterium labeled (R)-Zanubrutinib. (R)-Zanubrutinib is the R enantiomer of Zanubrutinib. Zanubrutinib is a selective Bruton tyrosine kinase (BTK) inhibitor.
    (R)-Zanubrutinib-d<sub>5</sub>
  • HY-W778511
    Levulinic acid-13C3
    Levulinic acid-13C3 (4-Oxovaleric acid-13C) is the 13C-labeled Levulinic acid (HY-Y0839). Levulinic acid is a precursor for the synthesis of biofuels, such as ethyl levulinate. Levulinic acid is also a 5-keto-pentanoic acid. Levulinic acid can be utilized by the cells as a cosubstrate for biopolymer synthesis. Levulinic acid can be used in antibacterial research.
    Levulinic acid-<sup>13</sup>C<sub>3</sub>
  • HY-139688S
    (±)-Voriconazole-d3
    (±)-Voriconazole-d3 is the deuterium labeled (±)-Voriconazole.
    (±)-Voriconazole-d<sub>3</sub>
  • HY-B1637S
    Ditiocarb-d10 sodium
    Ditiocarb-d10 sodium (Sodium diethyldithiocarbamate-d10) is the deuterium labeled Ditiocarb sodium (HY-B1637). Ditiocarb sodium (Sodium diethyldithiocarbamate) is an orally active copper reagent. Ditiocarb sodium exhibits activities such as antioxidation, chelation, anti-tumor effects, immunomodulation, and anti-HIV properties. Ditiocarb sodium can be used in the research of tumors, inflammatory, and immune-related diseases.
    Ditiocarb-d<sub>10</sub> sodium
  • HY-W143238S
    4-Hydroxybenzoic acid n-nonyl ester-d4
    4-Hydroxybenzoic acid n-nonyl ester-d4 is the deuterium labeled 4-Hydroxybenzoic acid n-nonyl ester.
    4-Hydroxybenzoic acid n-nonyl ester-d<sub>4</sub>
  • HY-B1204S4
    Histamine-15N3
    Histamine-15N3 is the 15N3-labeled Histamine (HY-B1204). Histamine is the agonist for histamine receptor and a vasodilator. Histamine is an organic nitrogen compound that participates in local immune responses, regulates intestinal physiological functions, and acts as a neurotransmitter. Histamine affects p38 MAPK/Akt signaling pathway, exhibits antitumor, antioxidant and anti-inflammatory activities. Histamine can be used in the research of acute myeloid leukemia, malignant melanoma, and renal cell carcinoma.
    Histamine-<sup>15</sup>N<sub>3</sub>
  • HY-W009658S
    1,1':2',1''-Terphenyl-d14
    		99%
    1,1':2',1''-Terphenyl-d14 is the deuterium labeled 1,1':2',1''-Terphenyl.
    1,1':2',1''-Terphenyl-d<sub>14</sub>
  • HY-B1315S1
    Carbaryl-d7
    		99%
    Carbaryl-d7 is the deuterium labeled Carbaryl (HY-B1315). Carbaryl is the inhibitor for acetylcholinesterase that inhibits the degradation of acetylcholine in the synaptic cleft, leads to the accumulation of acetylcholine and causes neurotoxicity. Carbaryl can be used as an insecticide.
    Carbaryl-d<sub>7</sub>
  • HY-W769319A
    Inosinic acid-13C5 TEA
    Inosinic acid-13C5 (5'-IMP-13C5) TEA is the 13C-labeled Inosinic acid (HY-108213). Inosinic acid is an endogenous metabolite. Inosinic acid is used as umami tastant, or as the dietary supplement to improve the yield and meat quality of pigs.
    Inosinic acid-<sup>13</sup>C<sub>5</sub> TEA
  • HY-W009142S
    Dicyclohexyl phthalate-d4
    Dicyclohexyl phthalate-d4 is the deuterium labeled Dicyclohexyl phthalate.
    Dicyclohexyl phthalate-d<sub>4</sub>
  • HY-B0147S1
    Pefloxacin-d3
    		99.35%
    Pefloxacin-d3 (Pefloxacinium-d3) is the deuterium labeled Pefloxacin (HY-B0147). Pefloxacin (Pefloxacinium) is a broad spectrum antibiotic. Pefloxacin blocks DNA replication by inhibiting DNA gyrase. Pefloxacin inhibits DNA relaxation catalyzed by topoisomerase I with an IC50 of 45 μg/mL. Pefloxacin exhibits antibacterial activity against Escherichia coli, Pseudomonas aeruginosa, and Bacteroides fragilis with MIC90s of 0.12, 4, and 16 mg/L, respectively. Pefloxacin has anti-Plasmodium yoelii infection activity. Pefloxacin increase UVA-induced edema and immunesuppression. Pefloxacin can be used for infection studies.
    Pefloxacin-d<sub>3</sub>
  • HY-76996S1
    (S)-5-Hydroxymethyl Tolterodine-d14 formate
    (S)-5-Hydroxymethyl Tolterodine-d14 (formate) is deuterium labeled (S)-2-(3-(diisopropylamino)-1-phenylpropyl)-4-(hydroxymethyl)phenol.
    (S)-5-Hydroxymethyl Tolterodine-d<sub>14</sub> formate
  • HY-N1201S1
    Apigenin-13C
    Apigenin-13C is the 13C-abeled Apigenin (HY-N1201). Apigenin is a competitive CYP2C9 inhibitor with a Ki of 2 μM.
    Apigenin-<sup>13</sup>C
  • HY-182521S
    17:0-22:4 DG-d5
    17:0-22:4 DG-d5 is the deuterium labeled 17:0-22:4 DG.
    17:0-22:4 DG-d<sub>5</sub>